An online atlas of human plasma metabolite signatures of gut microbiome composition

KF Dekkers, S Sayols-Baixeras, G Baldanzi… - Nature …, 2022 - nature.com
Human gut microbiota produce a variety of molecules, some of which enter the bloodstream
and impact health. Conversely, dietary or pharmacological compounds may affect the …

Comparison of fecal and blood metabolome reveals inconsistent associations of the gut microbiota with cardiometabolic diseases

K Deng, J Xu, L Shen, H Zhao, W Gou, F Xu… - Nature …, 2023 - nature.com
Blood metabolome is commonly used in human studies to explore the associations of gut
microbiota-derived metabolites with cardiometabolic diseases. Here, in a cohort of 1007 …

Multi-omics approaches for revealing the complexity of cardiovascular disease

S Doran, M Arif, S Lam, A Bayraktar… - Briefings in …, 2021 - academic.oup.com
The development and progression of cardiovascular disease (CVD) can mainly be attributed
to the narrowing of blood vessels caused by atherosclerosis and thrombosis, which induces …

Diagnostics and therapeutic implications of gut microbiota alterations in cardiometabolic diseases

GG Schiattarella, A Sannino, G Esposito… - Trends in cardiovascular …, 2019 - Elsevier
Alterations in gut microbiota composition and its metabolic activity are emerging as one of
the most powerful determinants of cardiovascular disease. Although our knowledge of the …

Combinatorial, additive and dose-dependent drug–microbiome associations

SK Forslund, R Chakaroun… - Nature, 2021 - nature.com
During the transition from a healthy state to cardiometabolic disease, patients become
heavily medicated, which leads to an increasingly aberrant gut microbiome and serum …

The metabolic role and therapeutic potential of the microbiome

LE Olofsson, F Bäckhed - Endocrine reviews, 2022 - academic.oup.com
We are host to an assembly of microorganisms that vary in structure and function along the
length of the gut and from the lumen to the mucosa. This ecosystem is collectively known as …

Interaction between gut microbiome and cardiovascular disease

J Peng, X Xiao, M Hu, X Zhang - Life Sciences, 2018 - Elsevier
Traditional cardiovascular risk factors do not underlie all incidence of cardiovascular
disease. In recent years, accumulating evidence has demonstrated that gut microbiota and …

Gut microbiome and cardiovascular diseases

N Yoshida, T Yamashita, K Hirata - Diseases, 2018 - mdpi.com
Recent evidence has suggested that the gut microbiome is involved in human health and
diseases, such as inflammatory bowel disease, liver cirrhosis, rheumatoid arthritis, and type …

A complex microworld in the gut: gut microbiota and cardiovascular disease connectivity

MR Howitt, WS Garrett - Nature medicine, 2012 - nature.com
Millions of healthy bacteria colonize our guts from the moment we are born. Changes in the
composition and abundance of these commensals affect the entire immune system and can …

Gut microbiota in cardiovascular disease and heart failure

T Kitai, WHW Tang - Clinical Science, 2018 - portlandpress.com
Accumulating evidence supports a relationship between the complexity and diversity of the
gut microbiota and host diseases. In addition to alterations in the gut microbial composition …