Nutrigenomics, the microbiome, and gene-environment interactions: new directions in cardiovascular disease research, prevention, and treatment: a scientific …
JF Ferguson, H Allayee, RE Gerszten… - Circulation …, 2016 - Am Heart Assoc
Cardiometabolic diseases are the leading cause of death worldwide and are strongly linked
to both genetic and nutritional factors. The field of nutrigenomics encompasses multiple …
to both genetic and nutritional factors. The field of nutrigenomics encompasses multiple …
Microbiome connections with host metabolism and habitual diet from 1,098 deeply phenotyped individuals
The gut microbiome is shaped by diet and influences host metabolism; however, these links
are complex and can be unique to each individual. We performed deep metagenomic …
are complex and can be unique to each individual. We performed deep metagenomic …
[HTML][HTML] Cross-omics analysis revealed gut microbiome-related metabolic pathways underlying atherosclerosis development after antibiotics treatment
BA Kappel, L De Angelis, M Heiser, M Ballanti… - Molecular …, 2020 - Elsevier
Objective The metabolic influence of gut microbiota plays a pivotal role in the pathogenesis
of cardiometabolic diseases. Antibiotics affect intestinal bacterial diversity, and long-term …
of cardiometabolic diseases. Antibiotics affect intestinal bacterial diversity, and long-term …
The gut microbiome modulates the protective association between a Mediterranean diet and cardiometabolic disease risk
To address how the microbiome might modify the interaction between diet and
cardiometabolic health, we analyzed longitudinal microbiome data from 307 male …
cardiometabolic health, we analyzed longitudinal microbiome data from 307 male …
[HTML][HTML] The gut microbiota (microbiome) in cardiovascular disease and its therapeutic regulation
In the last two decades, considerable interest has been shown in understanding the
development of the gut microbiota and its internal and external effects on the intestine, as …
development of the gut microbiota and its internal and external effects on the intestine, as …
The gut microbiome as novel cardio-metabolic target: the time has come!
S Vinjé, E Stroes, M Nieuwdorp… - European heart …, 2014 - academic.oup.com
Recent studies reveal a potential contribution of intestinal microbes in the expression of
certain human cardio-metabolic diseases. The mechanisms through which intestinal …
certain human cardio-metabolic diseases. The mechanisms through which intestinal …
Gut microbiota in cardiovascular health and disease
Significant interest in recent years has focused on gut microbiota–host interaction because
accumulating evidence has revealed that intestinal microbiota play an important role in …
accumulating evidence has revealed that intestinal microbiota play an important role in …
Intestinal Microbiota in Cardiovascular Health and Disease: JACC State-of-the-Art Review
WHW Tang, F Bäckhed, U Landmesser… - Journal of the American …, 2019 - jacc.org
Despite major strides in reducing cardiovascular disease (CVD) burden with modification of
classic CVD risk factors, significant residual risks remain. Recent discoveries that linked …
classic CVD risk factors, significant residual risks remain. Recent discoveries that linked …
The emerging role of gut microbial metabolism on cardiovascular disease
K Kasahara, FE Rey - Current opinion in microbiology, 2019 - Elsevier
Highlights•Clinical cohorts show associations between gut microbiome and CVD.•Products
of microbial metabolism derived from diet are linked with progression of CVD.•Microbes are …
of microbial metabolism derived from diet are linked with progression of CVD.•Microbes are …
[HTML][HTML] Metabolome–microbiome crosstalk and human disease
In this review, we discuss the growing literature demonstrating robust and pervasive
associations between the microbiome and metabolome. We focus on the gut microbiome …
associations between the microbiome and metabolome. We focus on the gut microbiome …