Potential impact and study considerations of metabolomics in cardiovascular health and disease: a scientific statement from the American Heart Association

S Cheng, SH Shah, EJ Corwin, O Fiehn… - Circulation …, 2017 - Am Heart Assoc
Through the measure of thousands of small-molecule metabolites in diverse biological
systems, metabolomics now offers the potential for new insights into the factors that …

[HTML][HTML] Far from the eyes, close to the heart: dysbiosis of gut microbiota and cardiovascular consequences

M Serino, V Blasco-Baque, S Nicolas… - Current cardiology …, 2014 - Springer
These days, the gut microbiota is universally recognized as an active organ that can
modulate the overall host metabolism by promoting multiple functions, from digestion to the …

The heart and gut relationship: a systematic review of the evaluation of the microbiome and trimethylamine-N-oxide (TMAO) in heart failure

KM Anderson, EP Ferranti, EC Alagha… - Heart Failure …, 2022 - Springer
There is an expanding body of research on the bidirectional relationship of the human gut
microbiome and cardiovascular disease, including heart failure (HF). Researchers are …

Atlas of gut microbe-derived products from aromatic amino acids and risk of cardiovascular morbidity and mortality

I Nemet, XS Li, A Haghikia, L Li, J Wilcox… - European Heart …, 2023 - academic.oup.com
Aims Precision microbiome modulation as a novel treatment strategy is a rapidly evolving
and sought goal. The aim of this study is to determine relationships among systemic gut …

Cross‐Talk between Gut Microbiota and Heart via the Routes of Metabolite and Immunity

J Bu, Z Wang - Gastroenterology research and practice, 2018 - Wiley Online Library
Considering the prevalence of cardiovascular disease (CVD), significant interest has been
focused on the gut microbiota‐heart interaction because the gut microbiota has been …

[HTML][HTML] Role of gut microbiota in cardiovascular diseases

M Novakovic, A Rout, T Kingsley, R Kirchoff… - World journal of …, 2020 - ncbi.nlm.nih.gov
The human gut is colonized by a community of microbiota, primarily bacteria, that exist in a
symbiotic relationship with the host. Intestinal microbiota-host interactions play a critical role …

Blood microbiota and circulating microbial metabolites in diabetes and cardiovascular disease

G Velmurugan, V Dinakaran, J Rajendhran… - Trends in Endocrinology …, 2020 - cell.com
Diabetes and cardiovascular disease (CVD) have evolved as the leading cause of mortality
and morbidity worldwide. In addition to traditional risk factors, recent studies have …

[HTML][HTML] The effects of the Green-Mediterranean diet on cardiometabolic health are linked to gut microbiome modifications: A randomized controlled trial

E Rinott, AY Meir, G Tsaban, H Zelicha, A Kaplan… - Genome medicine, 2022 - Springer
Background Previous studies have linked the Mediterranean diet (MED) with improved
cardiometabolic health, showing preliminary evidence for a mediating role of the gut …

[HTML][HTML] Multi-omic analysis of the microbiome and metabolome in healthy subjects reveals microbiome-dependent relationships between diet and metabolites

ZZ Tang, G Chen, Q Hong, S Huang, HM Smith… - Frontiers in …, 2019 - frontiersin.org
The human microbiome has been associated with health status, and risk of disease
development. While the etiology of microbiome-mediated disease remains to be fully …

Exploring the microbiome in heart failure

T Kitai, J Kirsop, WHW Tang - Current heart failure reports, 2016 - Springer
Recent years have brought interesting insights into the human gut microbiota and have
highlighted its increasingly recognized impact on cardiovascular (CV) diseases, including …