Purpose Abnormal platelet activation plays an important role in the development of sepsis.
The effect of antiplatelet drugs on the outcome of patients with sepsis remains unclear. This …

Background Acute respiratory distress syndrome (ARDS) results in significant hypoxia, and
ARDS is the central pathology of COVID-19. Inhaled prostacyclin has been proposed as a …

The acute respiratory distress syndrome (ARDS) is a clinical syndrome with primarily
supportive management options. Despite extensive basic and clinical investigations …

Introduction Ventilatory management and general supportive care of acute respiratory
distress syndrome (ARDS) in the adult population have led to significant clinical …

Acute respiratory distress syndrome (ARDS) is defined as a syndrome of acute onset, with
bilateral opacities on chest imaging and respiratory failure not caused by cardiac failure …

Disruption of the lung endothelial and epithelial barriers during acute inflammation leads to
excessive neutrophil migration. It is likely that activated platelets promote pulmonary …

Platelets play an important role in abdominal sepsis and P2Y12 receptor antagonists have
been reported to exert anti-inflammatory effects. Herein, we assessed the impact of platelet …

Since its first description, the acute respiratory distress syndrome (ARDS) has been
acknowledged to be a major clinical problem in respiratory medicine. From July 2015 to July …

The acute respiratory distress syndrome (ARDS) causes 40% mortality in approximately
200,000 critically ill patients annually in the United States. ARDS is caused by protein-rich …

Background There is no pharmacologic treatment for ARDS. Platelets play an important role
in the pathophysiology of ARDS. Preclinical, observational, and clinically relevant models of …