Regulatory mechanisms in the mixed lymphocyte reaction: evidence for the requirement of two T cells to interact in the generation of effective suppression.
G Chaouat, BJ Mathieson, R Asofsky - Journal of immunology …, 1982 - journals.aai.org
The cellular requirements for suppression of a mixed lymphocyte reaction (MLR) by in vivo
alloantigen-activated spleen cells were investigated. We found that the suppression was …
alloantigen-activated spleen cells were investigated. We found that the suppression was …
Suppression of the mixed lymphocyte reaction by alloantigen-primed and-stimulated human spleen lymphocytes.
AN Akbar, DB Jones - Immunology, 1984 - ncbi.nlm.nih.gov
This communication examines the ability of T cell-enriched preparations from human spleen
to suppress lymphocyte proliferation following activation in the mixed lymphocyte reaction …
to suppress lymphocyte proliferation following activation in the mixed lymphocyte reaction …
Induction of immunoglobulin-secreting cells in the allogeneic mixed leukocyte reaction: regulation by helper and suppressor lymphocyte subsets in man.
BL Kotzin, CJ Benike, EG Engleman - Journal of immunology …, 1981 - journals.aai.org
The existence of functionally distinct T lymphocyte subsets in man, initially demonstrated
with heteroantisera, has been confirmed with monoclonal reagents. Two major subsets have …
with heteroantisera, has been confirmed with monoclonal reagents. Two major subsets have …
REGULATORY MECHANISMS IN CELL-MEDIATED IMMUNE RESPONSES: I. Regulation of Mixed Lymphocyte Reactions by Alloantigen-Activated Thymus-Derived …
SS Rich, RR Rich - The Journal of Experimental Medicine, 1974 - rupress.org
Regulatory effects of alloantigen-activated thymus-derived lymphocytes in mixed lymphocyte
reactions have been demonstrated. Mice were injected into foot pads with allogeneic spleen …
reactions have been demonstrated. Mice were injected into foot pads with allogeneic spleen …
Immunoregulatory function of T cells activated in the autologous mixed lymphocyte reaction.
SP James, GG Yenokida, AS Graeff… - … (Baltimore, Md.: 1950 …, 1981 - journals.aai.org
This study was undertaken to define the functional properties of T cells stimulated in the
autologous mixed lymphocyte reaction (MLR) by purified B cells or macrophages. In …
autologous mixed lymphocyte reaction (MLR) by purified B cells or macrophages. In …
Suppression of in vitro CML generation by alloactivated lymphocytes: analysis of antigen-nonspecific suppressive mechanisms.
CG Orosz, RM Ferguson - Journal of immunology (Baltimore, Md …, 1985 - journals.aai.org
We have investigated the in vitro phenomena associated with antigen-nonspecific
suppression of mixed lymphocyte culture (MLC) responses by allocativated lymphocytes …
suppression of mixed lymphocyte culture (MLC) responses by allocativated lymphocytes …
Fractionation of lymphocyte subpopulations which regulate mixed lymphocyte reactions
RR Rich, L Chu, S Solliday Rich - Journal of Immunology, 1977 - journals.aai.org
Four days after injection of allogeneic lymphocytes BALB/c splenic T cells suppress
proliferation of syngeneic cells in mixed lymphocyte reactions (MLR). Conversely, lymph …
proliferation of syngeneic cells in mixed lymphocyte reactions (MLR). Conversely, lymph …
Specific loss of stimulator activity following mixed lymphocyte reactions is due to cytotoxic cells
CA Janeway Jr, DE Mosier… - European Journal of …, 1976 - Wiley Online Library
Experiments were performed to test the hypothesis that stimulating antigens in the mixed
lymphocyte reaction (MLR) are expressed in a restricted fashion on lymphocytes. Thus one …
lymphocyte reaction (MLR) are expressed in a restricted fashion on lymphocytes. Thus one …
Spleen cells from adult mice given total lymphoid irradiation (TLI) or from newborn mice have similar regulatory effects in the mixed leukocyte reaction (MLR). II …
S Okada, S Strober - Journal of immunology (Baltimore, Md.: 1950), 1982 - journals.aai.org
Spleen cells from newborn BALB/c mice were added to the mixed leukocyte reaction (MLR)
between a variety of responder and stimulator cells. The newborn cells nonspecifically …
between a variety of responder and stimulator cells. The newborn cells nonspecifically …
The human autologous mixed lymphocyte reaction. III. Immune circuits.
JS Smolen, TM Chused, EA Novotny… - Journal of immunology …, 1982 - journals.aai.org
The human autologous mixed lymphocyte reaction represents the proliferative response of T
cells to determinants presented on autologous non-T cells. Purified T4+ cells vigorously …
cells to determinants presented on autologous non-T cells. Purified T4+ cells vigorously …
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