For a small but important fraction of patients receiving mechanical ventilation, protracted
dependence on a ventilator entails serious hazard, disability, and cost. Most such patients …

Withdrawing invasive mechanical ventilation from patients who require ventilatory support is
one of the best studied areas in intensive care medicine. A series of studies dating back 25 …

PATIENTS who require mechanical ventilation will either be promptly weaned from the
ventilator and the endotracheal tube or require more prolonged ventilatory assistance by …

Multiple complications associated with mechanical ventilation mandate that clinicians
expeditiously define and reverse the pathophysiologic processes that precipitate respiratory …

In the practice of critical care, discontinuation of mechanical ventilation is an important
everyday clinical issue. Clinicians are often too conservative in their practice of liberating …

Weaning from mechanical ventilation—the process of preparing for and eventually carrying
out the removal of external ventilatory support—may be a simple task in patients with readily …

It is a pleasure and honor for me to give the 26th Annual Donald F Egan Scientific Lecture at
the American Association for Respiratory Care. Much of my research career has focused on …

Discontinuation of mechanical ventilation is too frequently difficult and frustrating for the
patient and the clinician alike. With the view that expeditious withdrawal of mechanical …

Preview Successful weaning of patients from ventilator support is not always easy. When
difficulty is expected or attempts have repeatedly failed, what approach should be used? In …

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