Background Environmental organic dust exposures enriched in Toll-like receptor (TLR)
agonists can reduce allergic asthma development but are associated with occupational …

The biological effects of acute particulate air pollution exposure in host innate immunity
remain obscure and have relied largely on in vitro models. We hypothesized that single …

Epidemiological studies have consistently shown associations between elevated
concentrations of urban particulate matter (UPM) air pollution and exacerbations of asthma …

Asian sand dust (ASD) is known to exacerbate asthma, although its mechanism is not yet
well understood. In this study, when the effects on inflammatory response by LPS present in …

The very low density lipoprotein receptor (VLDLR) is a member of the low-density lipoprotein
receptor family that binds multiple ligands and plays a key role in brain development …

The respiratory tract is under constant bombardment from both innocuous and pathogenic
material. The decision of how to respond to these challenges is mediated by a specialized …

Background Environmental co-exposure to allergen and traffic-related air pollution is
common globally and contributes to the exacerbation of respiratory diseases. Individual …

Air pollution contributes to acute exacerbations of asthma and the development of asthma in
children and adults. Airway epithelial cells interface innate and adaptive immune responses …

Background: Early microbial exposure may reduce the risk for developing allergies on an
atopic genetic background. Toll-like receptors (TLRs) recognize pathogen-associated …

Dendritic cells (DCs) play a crucial role in the initiation of immune responses against
infectious particles and tumor cells; however, the impact of age, anthropometric parameters …