Dendritic cells (DCs) lie at the heart of the innate immune system, specialised at recognising
danger signals in many forms including foreign material, infection or tissue damage and …

Oxidative stress is important in dendritic cell (DC) activation. Environmental particulate
matter (PM) directs pro-oxidant activities that may alter DC function. Nuclear erythroid 2 p45 …

Background: Pulmonary dendritic cells (DCs) play critical roles in both allergy and in viral
infection. Levels of cysteinyl leukotrienes (cysLTs) increase after allergen sensitization and …

Exposure to ambient particulate matter has been shown to promote a variety of disorders,
including cardiovascular diseases predominantly of ischemic etiology. However, the …

Background Accumulating evidence indicates that cells expressing Toll-like receptors
(TLRs) play an important role in allergic diseases. The authors undertook this study to …

Although reports suggest that dendritic cells (DC) are involved in the allergic reaction
characterized by a T helper cell type 2 (Th2) profile, the role of myeloid (M-DC) and …

Background and objective: Cigarette smoking is the main risk factor for the development of
chronic obstructive pulmonary disease (COPD). Recently, toll‐like receptor 3 (TLR3) was …

Very few transcription factors have been identified that are required by antigen‐presenting
cells (APCs) to induce T helper type 2 (Th2) responses. Because lung CD11b+ conventional …

In humans, environmental exposure to a high dose of lipopolysaccharide (LPS) protects
from allergic asthma, the immunological underpinnings of which are not well understood. In …

Smoking promotes the development of allergic asthma and pneumonia. Chlamydophila
pneumoniae lung infection is associated with an increased risk for asthma, inducing an …