Novel transplantation techniques are currently under development to preserve the function
of impaired tissues or organs. While current technologies can enhance the survival of …

Introduction Cell transplantation is a promising curative therapeutic strategy whereby
impaired organ function can be restored without the need for whole-organ transplantation. A …

Clinical islet transplantation is an effective therapy in restoring physiological glycemic
control in type 1 diabetics. However, allogeneic islets derived from cadaveric sources elicit …

Highlights•To successfully transplant islets, biomaterial design may offer a solution.•
Immunoisolation using semi-permeable barriers can remove broad immunosuppression.• …

An innovative immunosuppressant with a minimally invasive delivery system has emerged
in the biomedical field. The application of biodegradable and biocompatible polymer forms …

During autoimmunity or organ transplant rejection, the immune system attacks host or
transplanted tissue, causing debilitating inflammation for millions of patients. There is no …

Implantable biomaterials represent the forefront of regenerative medicine, providing
platforms and vessels for delivering a creative range of therapeutic benefits in diverse …

Controlled modulation of immune response, especially the balance between
immunostimulatory and immunosuppressive responses, is critical for a variety of clinical …

Autoimmune diseases, rejection of transplanted organs and grafts, chronic inflammatory
diseases, and immune‐mediated rejection of biologic drugs impact a large number of …

Type 1 diabetes mellitus (T1DM) is a chronic metabolic disease caused by the destruction of
pancreatic β‐cells in response to autoimmune reactions. Shapiro et al. conducted novel islet …