An investigation of the effect of sorafenib on tumour growth and recurrence after liver cancer resection in nude mice independent of phosphorylated extracellular …

Z Wang, J Hu, SJ Qiu, XW Huang, Z Dai… - Expert opinion on …, 2011 - Taylor & Francis
Objective: The goal of this study is to investigate the effects of sorafenib on tumor growth,
recurrence and metastasis after curative resection of liver cancer. Research methods …

AKR1B10 inhibitor enhances the inhibitory effect of sorafenib on liver cancer xenograft

YY Jin, C Han, N Geng, YR Li, LY Zheng… - Zhonghua gan Zang …, 2019 - europepmc.org
Objective: To investigate the inhibitory effect of AKR1B10 inhibitor combined with sorafenib
on hepatocellular carcinoma (HCC) xenograft growth. Methods: HepG2 xenograft model …

Sorafenib treatment on Chinese patients with advanced hepatocellular carcinoma: A study on prognostic factors of the viral and tumor status

SW Lee, TY Lee, YC Peng, SS Yang, HZ Yeh… - Medicine, 2019 - journals.lww.com
Sorafenib treatment on Chinese patients with advanced hepato... : Medicine Sorafenib
treatment on Chinese patients with advanced hepatocellular carcinoma: A study on prognostic …

Effect of sorafenib combined with cytostatic agents on hepatoblastoma cell lines and xenografts

C Eicher, A Dewerth, J Thomale, V Ellerkamp… - British journal of …, 2013 - nature.com
Background: Sorafenib has recently been shown to reduce tumour growth in
hepatoblastoma (HB) xenografts. The effect of a combined administration with cytostatic …

Differential combined effect of COX inhibitors on cell survival suppressed by sorafenib in the HepG2 cell line

K Yagi, Y Kawasaki, H Nakamura, T Miura… - Biological and …, 2014 - jstage.jst.go.jp
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths
worldwide. Sorafenib, a molecular-targeted drug, is a multi-target oral anti-neoplastic drug …

[HTML][HTML] Factors affecting therapeutic effects in 17 patients with advanced hepatocellular carcinoma who were treated with sorafenib for more than 12 months

K Katayama, R Kiyota, T Imai, Y Abe, T Nawa… - Case Reports in …, 2018 - karger.com
Abstract Background and Objective: Sorafenib is recommended for treating advanced
hepatocellular carcinoma. However, it is frequently discontinued because of adverse events …

Sorafenib potentiates irradiation effect in hepatocellular carcinoma in vitro and in vivo

W Yu, K Gu, Z Yu, D Yuan, M He, N Ma, S Lai, J Zhao… - Cancer letters, 2013 - Elsevier
The multikinase-inhibition action of sorafenib provides strong rationales for its combination
use with radiotherapy. We investigated the in vitro and in vivo effect of sorafenib combined …

Induction of Bim expression contributes to the antitumor synergy between sorafenib and mitogen-activated protein kinase/extracellular signal-regulated kinase kinase …

DL Ou, YC Shen, JD Liang, JY Liou, SL Yu… - Clinical Cancer …, 2009 - AACR
Purpose: Sorafenib has proved survival benefit for patients with advanced hepatocellular
carcinoma (HCC). This study explored whether the efficacy of sorafenib can be improved by …

Sorafenib combined with dasatinib therapy inhibits cell viability, migration, and angiogenesis synergistically in hepatocellular carcinoma

CC Cheng, WT Chao, JH Shih, YS Lai, YH Hsu… - Cancer Chemotherapy …, 2021 - Springer
Purpose Sorafenib is a multikinase inhibitor used for treatment of advanced hepatocellular
carcinoma. Sorafenib resistance may be related to Src-induced cell migration and …

The effects of sorafenib in healthy and cisplatin-treated rats

L DEMİRTAŞ, M Gürbüzel, H Tahirler… - Advances in Clinical …, 2023 - avesis.cu.edu.tr
Background. Sorafenib is a multikinase inhibitor currently used in the treatment of
hepatocellular carcinoma, renal cell carcinoma and thyroid cancer. Objectives. The literature …