In this study, we examined osteopontin (OPN) production in myeloma cells and plasma OPN
levels in multiple myeloma (MM) patients. We assessed OPN production in bone marrow …

Focal brain ischemia induces inflammation, extracellular matrix remodeling, gliosis, and
neovascularization. Osteopontin (OPN) is a secreted glycoprotein that has been implicated …

Background After an acute ischaemic stroke (AIS), several inflammatory biomarkers have
been investigated, but their predictive role on functional recovery remains to be validated …

Osteopontin (OPN) is a multi-functional cytokine which is involved in the pathogenesis of
autoimmune disease. We previously reported that thrombin-cleaved form of OPN plays a …

Objective. Osteopontin (OPN) is an extracellular matrix glycoprotein that has been
recognized as a potential inflammatory cytokine. The function of OPN is modulated by …

Osteopontin (OPN) is a proinflammatory cytokine that can be secreted from many cells,
including activated macrophages and T‐lymphocytes, and is widely distributed in many …

Osteopontin (OPN) and its receptors have been reported to be involved in a number of
autoimmune and inflammatory diseases. This study was designed to analyze the OPN …

Osteopontin (OPN) is a multifunctional protein which has shown neuroprotective properties
in animal models of cerebral ischemia. Nevertheless, its role in acute human stroke has not …

We have used in vitro oligodendrocyte differentiation and the in vivo remyelination model,
the cuprizone model, to identify genes regulating oligodendrocyte function and …

Objective The variety of disease phenotypes among patients with SLE challenges the
identification of new biomarkers reflecting disease activity and/or organ damage …