Proteins/peptides are generally much more sensitive to process‐or storage‐induced
degradations than small synthetic molecules. Therefore, significant efforts are needed to …

The success of most peptide and protein drugs is dependent upon the delivery of the
biologically active form to the site of action. In the design and development of formulations to …

Peptides are small polymers composed of 40 or fewer amino acids and are an increasingly
important class of drugs. Therapeutic peptides are less immunogenic and more economical …

Peptide drugs represent 5% of the global pharmaceutical market, but growing twice as fast
as the rest of the drug market. The development of peptide therapeutics is challenging due …

The purpose of this chapter is to provide practical guidance to formulation scientists charged
with the development of stable, manufacturable, and elegant solution dosage forms of …

In the early drug development phases covering preformulation and formulation
development, the physicochemical properties of the protein drug are assessed. Efforts are …

Publisher Summary This chapter discusses chemical and physical stability of
pharmaceuticals, the effect of formulation stabilizers on peptide stability and protein/peptide …

One of the challenges for the successful commercialization of therapeutic proteins is to
maintain the safety and efficacy of the protein during the manufacturing process, storage …

Part B explores protein degradation occuring in vivo during protein synthesis in cells,
examines the isolation and purification of proteins, details protein use in organisms, and …

Proteins and peptides are the building blocks of human body and act as the arsenal to
combat against the invading pathogenic organisms for treatment and management of …