Mitochondria are abundant in fully grown mammalian oocytes with a unique spherical
morphology, but the mechanisms controlling mitochondria behavior are not well understood …

Mitochondrial function, largely regulated by the dynamics of this organelle, is inextricably
linked to the oocyte health. In comparison with most somatic cells, mitochondria in oocytes …

Mitofusins (Mfn) are the important regulators of mitochondrial organization in mammalian
cells; however, their roles during oocyte development remain unknown. In the present study …

Mitochondria play many critical roles in cells, not only by supplying energy, but also by
supplying metabolites, buffering Ca2+ levels and regulating apoptosis. During oocyte …

Mitochondria are dynamic organelles that change their morphology by active fusion and
fission in response to cellular signaling and differentiation [1, 2]. The in vivo role of …

Abstract Mitofusin-2 (Mfn2) is essential for embryonic development, anti-apoptotic events,
protection against free radical-induced lesions and mitochondrial fusion in many cells …

Mitochondria change their shape through fusion and fission in order to adapt to their
metabolic milieu. Mitofusin-2 (MFN2) is a key regulatory protein in this process, mediating …

Mitochondrial fusion and fission (mitochondrial dynamics) are homeostatic processes that
safeguard normal cellular function. This relationship is especially strong in tissues with …

Mitochondria are dynamic organelles that continually adapt their structure through fusion
and fission in response to changes in their bioenergetic environment. Targeted deletion of …

Mitochondria are highly dynamic organelles and their distribution, structure and activity
affect a wide range of cellular functions. Mitochondrial membrane potential (∆ Ψm) is an …