DNA methylation changes in human lung epithelia cells exposed to multi-walled carbon nanotubes

MI Sierra, L Rubio, GF Bayón, I Cobo… - …, 2017 - Taylor & Francis
Humans are increasingly exposed to nanoparticles and, although many of their
physiological effects have been described, the molecular mechanisms underlying them are …

Differences in MWCNT-and SWCNT-induced DNA methylation alterations in association with the nuclear deposition

D Öner, M Ghosh, H Bové, M Moisse, B Boeckx… - Particle and fibre …, 2018 - Springer
Background Subtle DNA methylation alterations mediated by carbon nanotubes (CNTs)
exposure might contribute to pathogenesis and disease susceptibility. It is known that both …

[HTML][HTML] Multi-walled carbon nanotubes elicit concordant changes in DNA methylation and gene expression following long-term pulmonary exposure in mice

G Scala, MN Delaval, SP Mukherjee, A Federico… - Carbon, 2021 - Elsevier
Pulmonary exposure to multi-walled carbon nanotubes (MWCNTs) causes inflammation and
fibrosis. Our previous work has shown that industrially produced MWCNTs trigger specific …

[HTML][HTML] Single-walled and multi-walled carbon nanotubes induce sequence-specific epigenetic alterations in 16 HBE cells

M Ghosh, D Öner, RC Duca, B Bekaert… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Recent studies have identified carbon nanotube (CNT)-induced epigenetic changes as one
of the key players in patho-physiological response. In the present study, we investigated …

Multiwalled carbon nanotubes of varying size lead to DNA methylation changes that correspond to lung inflammation and injury in a mouse model

E Cole, JL Ray, S Bolten, RF Hamilton Jr… - Chemical Research …, 2019 - ACS Publications
Diversity in physicochemical properties of engineered multiwalled carbon nanotubes
(MWCNTs) increases the complexity involved in interpreting toxicity studies of these …

Alterations in DNA methylation corresponding with lung inflammation and as a biomarker for disease development after MWCNT exposure

TA Brown, JW Lee, A Holian, V Porter… - …, 2016 - Taylor & Francis
Use of multi-walled carbon nanotubes (MWCNT) is growing which increases occupational
exposures to these materials. Their toxic potential makes it important to have an in-depth …

Changes in DNA methylation induced by multi-walled carbon nanotube exposure in the workplace

M Ghosh, D Öner, K Poels, AM Tabish… - …, 2017 - Taylor & Francis
This study was designed to assess the epigenetic alterations in blood cells, induced by
occupational exposure to multi-wall carbon nanotubes (MWCNT). The study population …

Low-dose carbon-based nanoparticle-induced effects in A549 lung cells determined by biospectroscopy are associated with increases in genomic methylation

J Li, M Tian, L Cui, J Dwyer, NJ Fullwood, H Shen… - Scientific reports, 2016 - nature.com
Nanotechnology has introduced many manufactured carbon-based nanoparticles (CNPs)
into our environment, generating a debate into their risks and benefits. Numerous …

Titanium dioxide nanoparticles induce size-dependent cytotoxicity and genomic DNA hypomethylation in human respiratory cells

Y Ma, Y Guo, S Wu, Z Lv, Q Zhang, Y Ke - RSC advances, 2017 - pubs.rsc.org
The widespread use of titanium dioxide nanoparticles (TiO2 NPs) is gradually increasing the
risk of exposure to these potentially hazardous materials. Although numerous health effects …

Carbon nanotube-and asbestos-induced DNA and RNA methylation changes in bronchial epithelial cells

E Emerce, M Ghosh, D Öner, RC Duca… - Chemical Research …, 2019 - ACS Publications
Carbon nanotubes (CNTs) are nanoscale tube-shaped carbon materials used in many
industrial areas. Their fiber shape has caused concerns about their toxicity given their …