Plasma markers predict changes in amyloid, tau, atrophy and cognition in non-demented subjects

JB Pereira, S Janelidze, E Stomrud, S Palmqvist… - Brain, 2021 - academic.oup.com
It is currently unclear whether plasma biomarkers can be used as independent prognostic
tools to predict changes associated with early Alzheimer's disease. In this study, we sought …

The diagnostic and prognostic capabilities of plasma biomarkers in Alzheimer's disease

J Simrén, A Leuzy, TK Karikari, A Hye… - Alzheimer's & …, 2021 - Wiley Online Library
Introduction This study investigated the diagnostic and disease‐monitoring potential of
plasma biomarkers in mild cognitive impairment (MCI) and Alzheimer's disease (AD) …

Equivalence of plasma p‐tau217 with cerebrospinal fluid in the diagnosis of Alzheimer's disease

J Therriault, S Servaes, C Tissot… - Alzheimer's & …, 2023 - Wiley Online Library
INTRODUCTION Plasma biomarkers are promising tools for Alzheimer's disease (AD)
diagnosis, but comparisons with more established biomarkers are needed. METHODS We …

Plasma p-tau181 level predicts neurodegeneration and progression to Alzheimer's dementia: a longitudinal study

YL Wang, J Chen, ZL Du, H Weng, Y Zhang… - Frontiers in …, 2021 - frontiersin.org
Background: Plasma-based biomarkers would be potential biomarkers for early diagnosis of
Alzheimer's disease (AD) because they are more available and cost-effective than …

Plasma amyloid, tau, and neurodegeneration biomarker profiles predict Alzheimer's disease pathology and clinical progression in older adults without dementia

XN Shen, JQ Li, HF Wang, HQ Li… - Alzheimer's & …, 2020 - Wiley Online Library
Introduction Plasma markers have been reported to be associated with brain amyloid
burden, tau pathology, or neurodegeneration. We aimed to evaluate whether plasma …

Plasma biomarkers of Alzheimer's disease: a review of available assays, recent developments, and implications for clinical practice

MV Pais, OV Forlenza, BS Diniz - Journal of Alzheimer's …, 2023 - content.iospress.com
Recently, low-sensitive plasma assays have been replaced by new ultra-sensitive assays
such as single molecule enzyme-linked immunosorbent assay (Simoa), the Mesoscale …

Plasma biomarkers for Alzheimer's Disease in relation to neuropathology and cognitive change

DS Smirnov, NJ Ashton, K Blennow, H Zetterberg… - Acta …, 2022 - Springer
Plasma biomarkers related to amyloid, tau, and neurodegeneration (ATN) show great
promise for identifying these pathological features of Alzheimer's Disease (AD) as shown by …

Plasma p‐tau231, p‐tau181, PET biomarkers, and cognitive change in older adults

PF Meyer, NJ Ashton, TK Karikari… - Annals of …, 2022 - Wiley Online Library
Objective The objective of this study was to evaluate novel plasma p‐tau231 and p‐tau181,
as well as Aβ40 and Aβ42 assays as indicators of tau and Aβ pathologies measured with …

Specific associations between plasma biomarkers and postmortem amyloid plaque and tau tangle loads

G Salvadó, R Ossenkoppele, NJ Ashton… - EMBO molecular …, 2023 - embopress.org
Several promising plasma biomarkers for Alzheimer's disease have been recently
developed, but their neuropathological correlates have not yet been fully determined. To …

Plasma Aβ42/40 ratio alone or combined with FDG-PET can accurately predict amyloid-PET positivity: a cross-sectional analysis from the AB255 Study

V Pérez-Grijalba, J Arbizu, J Romero, E Prieto… - Alzheimer's research & …, 2019 - Springer
Background To facilitate population screening and clinical trials of disease-modifying
therapies for Alzheimer's disease, supportive biomarker information is necessary. This study …