Background: Frontotemporal dementia (FTD) in several 17q21-linked families was recently
explained by truncating mutations in the progranulin gene (GRN). Objective: To determine …

Abstract Objective Mutations in the Progranulin gene (PGRN) recently have been
discovered to be associated with frontotemporal dementia (FTD) linked to 17q21 without …

BACKGROUND: Frontotemporal dementia (FTD) is a neurodegenerative disease
characterized by cognitive impairment, language dysfunction, and/or changes in personality …

Frontotemporal dementia (FTD) is the second most frequent type of neurodegenerative
dementias. Mutations in the progranulin gene (GRN, PGRN) were recently identified in …

Null mutations in the progranulin gene (GRN, PGRN) were recently identified as the causal
mechanism underlying frontotemporal dementia (FTD) with ubiquitin‐positive brain …

Frontotemporal dementia (FTD), characterized by behavioural and language disorders, is a
clinically, genetically and pathologically heterogeneous group of diseases. The most …

Frontotemporal lobar degeneration (FTLD) recognises high familial incidence, with up to
50% of patients reported to have a family history of similar dementia. It has been reported …

Background Patients with frontotemporal dementia due to mutation of progranulin may have
a distinct phenotype. Objective To identify distinct clinical and pathologic features of patients …

Aims Frontotemporal lobar degeneration (FTLD) is a progressive neurodegenerative
disease and is the second most common form of young onset dementia after A lzheimer's …

Mutations in the progranulin (PGRN) gene have been identified as a cause of frontotemporal
dementia (FTD). However, little is known about the neuropsychological abilities of …