Challenges in the development and establishment of exosome-based drug delivery systems

J Wang, D Chen, EA Ho - Journal of Controlled Release, 2021 - Elsevier
Exosomes are extracellular vesicles released from cells and are characterized by a lipid
bilayer membrane encapsulating a variety of biological molecules such as nucleic acids or …

[HTML][HTML] Exosome-based drug delivery: translation from bench to clinic

HB Koh, HJ Kim, SW Kang, TH Yoo - Pharmaceutics, 2023 - mdpi.com
Exosome-based drug delivery is emerging as a promising field with the potential to
revolutionize therapeutic interventions. Exosomes, which are small extracellular vesicles …

Using exosomes, naturally-equipped nanocarriers, for drug delivery

EV Batrakova, MS Kim - Journal of Controlled Release, 2015 - Elsevier
Exosomes offer distinct advantages that uniquely position them as highly effective drug
carriers. Comprised of cellular membranes with multiple adhesive proteins on their surface …

Exosome engineering for efficient and targeted drug delivery: Current status and future perspective

F Malekian, A Shamsian, SP Kodam… - The Journal of …, 2023 - Wiley Online Library
Exosomes are membrane‐bound vesicles that are released by most cells. They carry
nucleic acids, cytokines, growth factors, proteins, lipids, and metabolites. They are …

[HTML][HTML] Exosomes as naturally occurring vehicles for delivery of biopharmaceuticals: insights from drug delivery to clinical perspectives

A Butreddy, N Kommineni, N Dudhipala - Nanomaterials, 2021 - mdpi.com
Exosomes as nanosized vesicles are emerging as drug delivery systems for therapeutics
owing to their natural origin, their ability to mediate intercellular communication, and their …

Exosomes as a next-generation drug delivery system: An update on drug loading approaches, characterization, and clinical application challenges

F Mehryab, S Rabbani, S Shahhosseini, F Shekari… - Acta biomaterialia, 2020 - Elsevier
Exosomes are small nanoparticles secreted by almost all cells and have a well-known role
in intercellular communication. They are found in different body fluids and can also be …

Exosomes as drug delivery systems: A brief overview and progress update

SM Patil, SS Sawant, NK Kunda - European Journal of Pharmaceutics and …, 2020 - Elsevier
Exosomes are intracellular membrane-based vesicles with diverse compositions that are
involved in biological and pathological processes. Since the discovery of exosomes, they …

[HTML][HTML] Engineering exosomes as refined biological nanoplatforms for drug delivery

X Luan, K Sansanaphongpricha, I Myers… - Acta Pharmacologica …, 2017 - nature.com
Exosomes, a subgroup of extracellular vesicles (EVs), have been recognized as important
mediators of long distance intercellular communication and are involved in a diverse range …

Exosomes: Large-scale production, isolation, drug loading efficiency, and biodistribution and uptake

I Kimiz-Gebologlu, SS Oncel - Journal of Controlled Release, 2022 - Elsevier
Exosomes are nanovesicles with different contents that play a role in various biological and
pathological processes. It offers significant advantages over other delivery systems such as …

[HTML][HTML] Encapsulation and assessment of therapeutic cargo in engineered exosomes: a systematic review

Z Chen, M Xiong, J Tian, D Song, S Duan… - Journal of …, 2024 - Springer
Exosomes are nanoscale extracellular vesicles secreted by cells and enclosed by a lipid
bilayer membrane containing various biologically active cargoes such as proteins, lipids …