High density lipoprotein biogenesis, cholesterol efflux, and immune cell function

MG Sorci-Thomas, MJ Thomas - Arteriosclerosis, thrombosis, and …, 2012 - Am Heart Assoc
This review provides a summary of recent research on the role of high-density lipoprotein
(HDL)/apolipoprotein AI cholesterol efflux and immune cell function. Plasma concentrations …

[HTML][HTML] High-density lipoproteins and immune response: A review

E Grao-Cruces, S Lopez-Enriquez, ME Martin… - International Journal of …, 2022 - Elsevier
High-density lipoproteins (HDLs) are heterogeneous lipoproteins that modify their
composition and functionality depending on physiological or pathological conditions. The …

[HTML][HTML] High density lipoproteins and atherosclerosis: emerging aspects

F Sala, AL Catapano, GD Norata - Journal of geriatric cardiology …, 2012 - ncbi.nlm.nih.gov
High density lipoproteins (HDL) promote the efflux of excess cholesterol from peripheral
tissues to the liver for excretion. This ability is responsible for the most relevant anti …

The role of high‐density lipoprotein in the regulation of the immune response: implications for atherosclerosis and autoimmunity

M Fernandes das Neves, JR Batuca… - …, 2021 - Wiley Online Library
Inflammation and immune dysfunction have been increasingly recognized as crucial
mechanisms in atherogenesis. Modifications in cell lipid metabolism, plasma dyslipidaemia …

Dysfunctional HDL and atherosclerotic cardiovascular disease

RS Rosenson, HB Brewer Jr, BJ Ansell… - Nature reviews …, 2016 - nature.com
High-density lipoproteins (HDLs) protect against atherosclerosis by removing excess
cholesterol from macrophages through the ATP-binding cassette transporter A1 (ABCA1) …

Apolipoprotein AI and HDL3 inhibit spreading of primary human monocytes through a mechanism that involves cholesterol depletion and regulation of CDC42

W Diederich, E Orso, W Drobnik, G Schmitz - Atherosclerosis, 2001 - Elsevier
The objective of the current study was to characterize the influence of high density
lipoproteins (HDL) on processes related to the vascular recruitment of human monocytes …

Role of HDL, ABCA1, and ABCG1 transporters in cholesterol efflux and immune responses

L Yvan-Charvet, N Wang, AR Tall - … , thrombosis, and vascular …, 2010 - Am Heart Assoc
Atherosclerosis has been characterized as a chronic inflammatory response to cholesterol
deposition in arteries, but the mechanisms linking cholesterol accumulation in macrophage …

Clinical significance of High-Density lipoproteins and the development of atherosclerosis: focus on the role of the adenosine triphosphate–Binding cassette protein A1 …

HB Brewer Jr, S Santamarina-Fojo - The American journal of cardiology, 2003 - Elsevier
Low levels of high-density lipoprotein (HDL) cholesterol constitute a risk factor for coronary
artery disease, and there is evidence that increasing HDL cholesterol levels reduces …

High-density lipoprotein function, dysfunction, and reverse cholesterol transport

EA Fisher, JE Feig, B Hewing, SL Hazen… - … , and vascular biology, 2012 - Am Heart Assoc
Although high high-density lipoprotein (HDL)-cholesterol levels are associated with
decreased cardiovascular risk in epidemiological studies, recent genetic and …

HDL and cardiovascular disease: atherogenic and atheroprotective mechanisms

M Navab, ST Reddy, BJ Van Lenten… - Nature Reviews …, 2011 - nature.com
The lipoprotein HDL has two important roles: first, it promotes reverse cholesterol transport,
and second, it modulates inflammation. Epidemiological studies show that HDL-cholesterol …