Despite enormous international efforts, skin melanoma is still a major clinical challenge.
Melanoma takes a top place among the most common cancer types and it has one of the …

In the initial period after melanoma was recognised as a disease entity in the early 1800's, it
was subclassified on the basis of its presumed origin (from a precursor naevus, from a …

The incidence of melanoma is increasing at one of the highest rates of any form of cancer in
the United States, with the current lifetime risk being one in 68. At present, there are limited …

The past decade has revealed that melanoma is comprised of multiple subclasses that can
be categorized on the basis of key features, including the clinical stage of disease, the …

Outcomes for patients with melanoma have improved over the past decade with the clinical
development and approval of immunotherapies targeting immune checkpoint receptors such …

Malignant melanoma is one of the most common cancers in the world. In the disease's early
stages, treatment involves surgery, in advanced stages however, treatment options were …

Cutaneous melanoma is the main cause of death for skin cancer. The majority of patients
with a diagnosis of melanoma have localized disease, which can be successfully treated …

Malignant melanoma presents a substantial clinical challenge. Current diagnostic methods
are limited in their ability to diagnose early disease and accurately predict individual risk of …

Melanoma is a malignant tumor which is inclined to metastasize promptly into the lymphatic
system and other organs such as lung, liver, brain or bone. Therefore early diagnosis …

Recent insights into the genetic and somatic aberrations have initiated a new era of rapidly
evolving targeted and immune-based treatments for melanoma. After decades of …