Nutritional control of immunity: Balancing the metabolic requirements with an appropriate immune function

V De Rosa, M Galgani, M Santopaolo… - Seminars in …, 2015 - Elsevier
The immune system is a highly integrated network of cells sensitive to a number of
environmental factors. Interestingly, recent years have seen a dramatic increase in our …

[PDF][PDF] Metabolic adaptation of lymphocytes in immunity and disease

NM Chapman, H Chi - Immunity, 2022 - cell.com
Adaptive immune responses mediated by T cells and B cells are crucial for protective
immunity against pathogens and tumors. Differentiation and function of immune cells require …

[HTML][HTML] The role of cell metabolism in innate immune memory

AV Ferreira, J Domiguéz-Andrés… - Journal of Innate Immunity, 2022 - karger.com
Immunological memory is classically attributed to adaptive immune responses, but recent
studies have shown that challenged innate immune cells can display long-term functional …

Nutrients and their role in host resistance to infection

CJ Field, IR Johnson, PD Schley - Journal of leukocyte biology, 2002 - academic.oup.com
Almost all nutrients in the diet play a crucial role in maintaining an “optimal” immune
response, such that deficient and excessive intakes can have negative consequences on …

[HTML][HTML] Immunometabolism of macrophages in bacterial infections

G Galli, M Saleh - Frontiers in Cellular and Infection Microbiology, 2021 - frontiersin.org
Macrophages are important effectors of tissue homeostasis, inflammation and host defense.
They are equipped with an arsenal of pattern recognition receptors (PRRs) necessary to …

Arginine metabolism in bacterial pathogenesis and cancer therapy

L Xiong, JLL Teng, MG Botelho, RC Lo… - International journal of …, 2016 - mdpi.com
Antibacterial resistance to infectious diseases is a significant global concern for health care
organizations; along with aging populations and increasing cancer rates, it represents a …

[PDF][PDF] Modification of proteins by metabolites in immunity

C Diskin, TAJ Ryan, LAJ O'neill - Immunity, 2021 - cell.com
Immunometabolism has emerged as a key focus for immunologists, with metabolic change
in immune cells becoming as important a determinant for specific immune effector …

Metabolism in type 2 immune responses

AM Kabat, EL Pearce, EJ Pearce - Immunity, 2023 - cell.com
The immune response is tailored to the environment in which it takes place. Immune cells
sense and adapt to changes in their surroundings, and it is now appreciated that in addition …

Immunometabolism: cellular metabolism turns immune regulator

RM Loftus, DK Finlay - Journal of Biological Chemistry, 2016 - ASBMB
Immune cells are highly dynamic in terms of their growth, proliferation, and effector functions
as they respond to immunological challenges. Different immune cells can adopt distinct …

Physiology and pathology of innate immune response against pathogens

JL Muñoz Carrillo, FP Castro García… - 2017 - ricaxcan.uaz.edu.mx
Pathogen infections are recognized by the immune system, which consists of two types of
responses: an innate immune response and an antigen-specific adaptive immune response …