The Capsular Polysaccharide Obstructs Wall Teichoic Acid Functions in Staphylococcus aureus

E Lehmann, R van Dalen, L Gritsch… - The Journal of …, 2024 - academic.oup.com
Background The cell envelope of Staphylococcus aureus contains two major secondary cell
wall glycopolymers: capsular polysaccharide (CP) and wall teichoic acid (WTA). Both the CP …

Function and regulation of Staphylococcus aureus wall teichoic acids and capsular polysaccharides

D Keinhoerster, SE George, C Weidenmaier… - International Journal of …, 2019 - Elsevier
Staphylococcus aureus produces different secondary cell wall glycopolymers such as wall
teichoic acids (WTA) and capsular polysaccharides (CP). These structures play an important …

Wall teichoic acid in Staphylococcus aureus host interaction

R van Dalen, A Peschel, NM van Sorge - Trends in microbiology, 2020 - cell.com
Staphylococcus aureus is a major opportunistic human pathogen that frequently causes
disease in community and hospital settings. Nasal colonization is an important risk factor for …

The staphylococcal surface-glycopolymer wall teichoic acid (WTA) is crucial for complement activation and immunological defense against Staphylococcus aureus …

K Kurokawa, K Takahashi, BL Lee - Immunobiology, 2016 - Elsevier
Staphylococcus aureus is a Gram-positive bacterial pathogen that is decorated by
glycopolymers, including wall teichoic acid (WTA), peptidoglycan, lipoteichoic acid, and …

Lack of Wall Teichoic Acids in Staphylococcus aureus Leads to Reduced Interactions with Endothelial Cells and to Attenuated Virulence in a Rabbit Model of …

C Weidenmaier, A Peschel, YQ Xiong… - Journal of infectious …, 2005 - academic.oup.com
Wall teichoic acids (WTAs) are major surface components of gram-positive bacteria that
have recently been shown to play a key role in nasal colonization by Staphylococcus …

Wall teichoic acids mediate increased virulence in Staphylococcus aureus

S Wanner, J Schade, D Keinhörster, N Weller… - Nature …, 2017 - nature.com
Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) are the
cause of a severe pandemic consisting primarily of skin and soft tissue infections. The …

Staphylococcus aureus Capsular Polysaccharides

K O'Riordan, JC Lee - Clinical microbiology reviews, 2004 - Am Soc Microbiol
Serotype 5 and 8 capsular polysaccharides predominate among clinical isolates of
Staphylococcus aureus. The results of experiments in animal models of infection have …

The wall teichoic acid and lipoteichoic acid polymers of Staphylococcus aureus

G Xia, T Kohler, A Peschel - International Journal of Medical Microbiology, 2010 - Elsevier
Staphylococci and most other Gram-positive bacteria incorporate complex teichoic acid (TA)
polymers into their cell envelopes. Several crucial roles in Staphylococcus aureus fitness …

Extensive remodelling of the cell wall during the development of Staphylococcus aureus bacteraemia

EJA Douglas, N Palk, T Brignoli, D Altwiley, M Boura… - Elife, 2023 - elifesciences.org
The bloodstream represents a hostile environment that bacteria must overcome to cause
bacteraemia. To understand how the major human pathogen Staphylococcus aureus …

Structural rationale for the modulation of abscess formation by Staphylococcus aureus capsular polysaccharides

AO Tzianabos, JY Wang… - Proceedings of the …, 2001 - National Acad Sciences
Staphylococcus aureus is a medically important bacterial pathogen that is a common cause
of superficial and deep-seated abscesses in humans. Most S. aureus isolates produce either …