Autofluorescence and diffuse reflectance spectroscopy and spectral imaging for breast surgical margin analysis
MD Keller, SK Majumder, MC Kelley… - Lasers in Surgery …, 2010 - Wiley Online Library
Abstract Background and Objective Most women with early stage breast cancer have the
option of breast conserving therapy, which involves a partial mastectomy for removal of the …
option of breast conserving therapy, which involves a partial mastectomy for removal of the …
Auto-fluorescence lifetime and light reflectance spectroscopy for breast cancer diagnosis: potential tools for intraoperative margin detection
V Sharma, S Shivalingaiah, Y Peng, D Euhus… - Biomedical optics …, 2012 - opg.optica.org
This study investigates the use of two spectroscopic techniques, auto-fluorescence lifetime
measurement (AFLM) and light reflectance spectroscopy (LRS), for detecting invasive ductal …
measurement (AFLM) and light reflectance spectroscopy (LRS), for detecting invasive ductal …
[HTML][HTML] Intra-operative spectroscopic assessment of surgical margins during breast conserving surgery
Background In over 20% of breast conserving operations, postoperative pathological
assessment of the excised tissue reveals positive margins, requiring additional surgery …
assessment of the excised tissue reveals positive margins, requiring additional surgery …
[HTML][HTML] Optical breast cancer margin assessment: an observational study of the effects of tissue heterogeneity on optical contrast
S Kennedy, J Geradts, T Bydlon, JQ Brown… - Breast Cancer …, 2010 - Springer
Introduction Residual cancer following breast conserving surgery increases the risk of local
recurrence and mortality. Margin assessment presents an unmet clinical need. Breast tissue …
recurrence and mortality. Margin assessment presents an unmet clinical need. Breast tissue …
Fat/water ratios measured with diffuse reflectance spectroscopy to detect breast tumor boundaries
LL De Boer, BG Molenkamp, TM Bydlon… - Breast cancer research …, 2015 - Springer
Recognition of the tumor during breast-conserving surgery (BCS) can be very difficult and
currently a robust method of margin assessment for the surgical setting is not available. As a …
currently a robust method of margin assessment for the surgical setting is not available. As a …
Performance metrics of an optical spectral imaging system for intra-operative assessment of breast tumor margins
TM Bydlon, SA Kennedy, LM Richards, JQ Brown… - Optics express, 2010 - opg.optica.org
As many as 20-70% of patients undergoing breast conserving surgery require repeat
surgeries due to a close or positive surgical margin diagnosed post-operatively [1]. Currently …
surgeries due to a close or positive surgical margin diagnosed post-operatively [1]. Currently …
Rapid noninvasive optical imaging of tissue composition in breast tumor margins
BACKGROUND: In women undergoing breast conserving surgery (BCS), up to 60% can
require re-excision. Our objective is to develop an optically based technology which can …
require re-excision. Our objective is to develop an optically based technology which can …
Scatter spectroscopic imaging distinguishes between breast pathologies in tissues relevant to surgical margin assessment
AM Laughney, V Krishnaswamy, EJ Rizzo… - Clinical Cancer …, 2012 - AACR
Purpose: A new approach to spectroscopic imaging was developed to detect and
discriminate microscopic pathologies in resected breast tissues; diagnostic performance of …
discriminate microscopic pathologies in resected breast tissues; diagnostic performance of …
[HTML][HTML] Towards the use of diffuse reflectance spectroscopy for real-time in vivo detection of breast cancer during surgery
LL De Boer, TM Bydlon, F Van Duijnhoven… - Journal of translational …, 2018 - Springer
Background Breast cancer surgeons struggle with differentiating healthy tissue from cancer
at the resection margin during surgery. We report on the feasibility of using diffuse …
at the resection margin during surgery. We report on the feasibility of using diffuse …
Autofluorescence and diffuse reflectance properties of malignant and benign breast tissues
TM Breslin, F Xu, GM Palmer, C Zhu… - Annals of Surgical …, 2004 - Springer
Background Fluorescence spectroscopy is an evolving technology that can rapidly
differentiate between benign and malignant tissues. These differences are thought to be due …
differentiate between benign and malignant tissues. These differences are thought to be due …
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- auto fluorescence reflectance spectroscopy
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- real time reflectance spectroscopy
- breast pathologies margin assessment
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- spectroscopic imaging margin assessment