ABSTRACT A hierarchy of heterochronic genes, lin-4, lin-14, lin-28 and lin-29, temporally
restricts terminal differentiation of Caenorhabditis elegans hypodermal seam cells to the …

The heterochronic genes lin-4, lin-14, lin-28, and lin-29 specify the timing of lateral
hypodermal seam cell terminal differentiation in Caenorhabditis elegans. We devised a …

The Caenorhabditis elegans gene lin-29 is required for the terminal differentiation of the
lateral hypodermal seam cells during the larval-to-adult molt. We find that lin-29 protein …

In Caenorhabditis elegans, the terminal differentiation of the hypodermal cells occurs at the
larval-to-adult molt, and is characterized in part by the formation of a morphologically distinct …

During postembryonic development of Caenorhabditis elegans, the heterochronic gene lin-
14 controls the timing of developmental events in diverse cell types. Three alternative lin-14 …

The heterochronic genes lin-4, lin-14,/in-28, and lin-29 control the timing of specific
postembryonic developmental events in C. elegans. The experiments described here …

The heterochronic gene lin-14 controls the temporal sequence of developmental events in
the C. elegans postembryonic cell lineage. It encodes a nuclear protein that is normally …

In Caenorhabditis elegans, a well-defined pathway of heterochronic genes ensures the
proper timing of stage-specific developmental events. During the final larval stage, an …

During wild-type development, a protein product of the Caenorhabditis elegans
heterochronic gene lin-14 is localized to nuclei of specific somatic cells in embryos and early …

Heterochronic genes form a regulatory pathway that controls the temporal sequence of the
Caenorhabditis elegans postembryonic cell lineage. One of these genes, lin-14, encodes a …