It is currently recognized that perpetual cross talk among key players in tumor
microenvironment such as cancer cells (CCs), cancer associated fibroblasts (CAFs), and …

Cancer-associated fibroblasts (CAFs) are a major constituent of the tumor microenvironment
(TME) and an important contributor to cancer progression and therapeutic resistance …

The tumor microenvironment (TME) plays a key role in the poor prognosis of many cancers.
However, there is a knowledge gap concerning how multicellular communication among the …

The inhibition of the binding between VEGFs and their receptors reduces angiogenesis and
retards tumor growth. Owing to the large amount of antibodies required, the antibody-based …

Gold nanoparticles (AuNPs) are a promising nanomaterial due to their drug-delivery
properties and inherent anti-neoplastic activity. Here, we focused on the anti-neoplastic …

Delivering cancer therapeutics to tumors necessitates their escape from the surrounding
blood vessels. Tumor vasculatures are not always sufficiently leaky. Herein, we engineer …

Here, we report an intrinsic property of gold nanoparticles (nanogold): they can interact
selectively with heparin-binding glycoproteins and inhibit their activity. Gold nanoparticles …

Angiogenesis is a process by which vessels are formed through preexisting ones, and this
plays a key role in the progression of solid tumors. However, tumor vessels are influenced …

Tumor angiogenesis is a complicated process based upon a sequence of interactions
between tumor and vessel endothelial cells. Tumor conditioned medium has been widely …

The early stages of angiogenesis can be divided into three steps: endothelial cell
proliferation, migration, and tube formation. Vascular endothelial growth factor (VEGF) is …