The application of metabolomics in translational research suffers from several technological
bottlenecks, such as data reproducibility issues and the lack of standardization of sample …

Metabolomics is the untargeted measurement of the metabolome, which is composed of the
complement of small molecules detected in a biological sample. As such, metabolomic …

Background Non-targeted metabolomics based on mass spectrometry enables high-
throughput profiling of the metabolites in a biological sample. The large amount of data …

Targeted metabolomics has significant advantages for quantification but suffers from
reduced metabolite coverage. In this study, we developed a large-scale targeted …

Metabolomics is the comprehensive assessment of endogenous metabolites and attempts to
systematically identify and quantify metabolites from a biological sample. Small-molecule …

A critical question facing the field of metabolomics is whether data obtained from different
centers can be effectively compared and combined. An important aspect of this is the …

Metabolomics has evolved as a discipline from a discovery and functional genomics tool,
and is now a cornerstone in the era of big data-driven precision medicine. Sample …

Metabolomics is the newest addition to the “omics” disciplines and has shown rapid growth
in its application to human health research because of fundamental advancements in …

The study of metabolism has had a long history. Metabolomics, a systems biology discipline
representing analysis of known and unknown pathways of metabolism, has grown …

Metabolomics analysis generates vast arrays of data, necessitating comprehensive
workflows involving expertise in analytics, biochemistry and bioinformatics in order to …