Mesenchymal stromal cells for acute respiratory distress syndrome (ARDS), sepsis, and COVID-19 infection: optimizing the therapeutic potential

E Gorman, J Millar, D McAuley… - Expert review of …, 2021 - Taylor & Francis
Introduction: Mesenchymal stromal (stem) cell (MSC) therapies are emerging as a promising
therapeutic intervention in patients with Acute Respiratory Distress Syndrome (ARDS) and …

[HTML][HTML] Current status of cell-based therapies for COVID-19: evidence from mesenchymal stromal cells in sepsis and ARDS

Z Xu, Y Huang, J Zhou, X Deng, W He, X Liu… - Frontiers in …, 2021 - frontiersin.org
The severe respiratory consequences of the coronavirus disease 2019 (COVID-19)
pandemic have prompted the urgent need for novel therapies. Cell-based therapies …

[HTML][HTML] Recent insights: mesenchymal stromal/stem cell therapy for acute respiratory distress syndrome

S Horie, JG Laffey - F1000Research, 2016 - ncbi.nlm.nih.gov
Acute respiratory distress syndrome (ARDS) causes respiratory failure, which is associated
with severe inflammation and lung damage and has a high mortality and for which there is …

[HTML][HTML] Cell-based Therapies for Acute Respiratory Distress Syndrome: Where Are We Now?

GF Curley, CM O'Kane, DF McAuley… - American Journal of …, 2024 - atsjournals.org
There is considerable interest in the potential for cell-based therapies, particularly
mesenchymal stromal cells (MSCs) and their products, as a therapy for acute respiratory …

Mesenchymal stromal cells for sepsis and septic shock: lessons for treatment of COVID-19

C Laroye, S Gibot, C Huselstein… - Stem cells …, 2020 - academic.oup.com
Sepsis is defined as life-threatening organ dysfunction caused by a deregulated immune
host response to infection. The emergence of the severe acute respiratory syndrome …

[HTML][HTML] Mesenchymal stem cells: current clinical progress in ARDS and COVID-19

K Xiao, F Hou, X Huang, B Li, ZR Qian, L Xie - Stem Cell Research & …, 2020 - Springer
Acute respiratory distress syndrome (ARDS) develops rapidly and has a high mortality rate.
Survivors usually have low quality of life. Current clinical management strategies are …

Concise review: mesenchymal stromal cell-based approaches for the treatment of acute respiratory distress and sepsis syndromes

CL Johnson, Y Soeder… - Stem cells translational …, 2017 - academic.oup.com
Despite extensive research on candidate pharmacological treatments and a significant and
increasing prevalence, sepsis syndrome, and acute respiratory distress syndrome (ARDS) …

Therapeutic potential and mechanisms of action of mesenchymal stromal cells for acute respiratory distress syndrome

GF Curley, JA Scott, JG Laffey - Current stem cell research & …, 2014 - ingentaconnect.com
Mesenchymal stem/stromal cells (MSCs) have become the focus of intense research effort
over the past 10 years, in an effort to harness their regenerative and immune-modulating …

[HTML][HTML] The safety and efficacy of mesenchymal stromal cells in ARDS: a meta-analysis of randomized controlled trials

F Wang, Y Li, B Wang, J Li, Z Peng - Critical Care, 2023 - Springer
Mesenchymal stromal cells (MSC) have shown potential efficacy in both animal and human
trials of acute respiratory distress syndrome (ARDS). Especially during the COVID-19 …

[HTML][HTML] Mesenchymal stromal cells as potential immunomodulatory players in severe acute respiratory distress syndrome induced by SARS-CoV-2 infection

P Mallis, E Michalopoulos… - World Journal of Stem …, 2020 - ncbi.nlm.nih.gov
Severe acute respiratory syndrome coronavirus-2 and the related coronavirus disease-19
(COVID-19) is a worldwide emerging situation, which was initially reported in December …