Hearing loss: mechanisms revealed by genetics and cell biology

AA Dror, KB Avraham - Annual review of genetics, 2009 - annualreviews.org
Hearing loss (HL), or deafness in its most severe form, affects an estimated 28 and 22.5
million Americans and Europeans, respectively. The numbers are higher in regions such as …

Genetics of hearing and deafness

S Angeli, X Lin, XZ Liu - The Anatomical Record: Advances in …, 2012 - Wiley Online Library
This article is a review of the genes and genetic disorders that affect hearing in humans and
a few selected mouse models of deafness. Genetics is playing an increasingly critical role in …

Hereditary hearing loss: from human mutation to mechanism

DR Lenz, KB Avraham - Hearing research, 2011 - Elsevier
The genetic heterogeneity of hereditary hearing loss is thus far represented by hundreds of
genes encoding a large variety of proteins. Mutations in these genes have been discovered …

The fundamental and medical impacts of recent progress in research on hereditary hearing loss

V Kalatzis, C Petit - Human molecular genetics, 1998 - academic.oup.com
What would define real progress in the field of deafness research in fundamental and
medical terms? In fundamental terms, progress would be measured by an improvement in …

Hereditary hearing loss; about the known and the unknown

H Kremer - Hearing research, 2019 - Elsevier
Hereditary hearing loss is both clinically and genetically very heterogeneous. Despite the
large number of genes that have been associated with the condition, many cases remain …

Non-syndromic hereditary sensorineural hearing loss: review of the genes involved

F Stelma, MF Bhutta - The Journal of Laryngology & Otology, 2014 - cambridge.org
Background: Hereditary sensorineural hearing loss is the most frequently occurring birth
defect. It has profound effects for the individual and is a substantial burden on society …

[HTML][HTML] Clinical aspects of hereditary hearing loss

A Kochhar, MS Hildebrand, RJH Smith - Genetics in Medicine, 2007 - Elsevier
Hearing loss is an etiologically diverse condition with many disease-related complications
and major clinical, social, and quality of life implications. As the rate of acquired hearing loss …

Histopathology and molecular genetics of hearing loss in the human

JB Nadol Jr, SN Merchant - International journal of pediatric …, 2001 - Elsevier
Hearing loss is among the most common disabilities of man. It has been estimated that over
70 million individuals in the world are hearing impaired with pure tone averages greater …

Genetics of hearing loss: syndromic

T Koffler, K Ushakov, KB Avraham - Otolaryngologic Clinics of …, 2015 - oto.theclinics.com
Hearing loss (HL) is the most prevalent sensory impairment in both childhood and
adulthood. 1, 2 According to the last update of the World Health Organization (WHO) …

Hereditary non-syndromic sensorineural hearing loss: transforming silence to sound

I Schrijver - The Journal of molecular diagnostics, 2004 - Elsevier
Tremendous progress has been made in our understanding of the molecular basis of
hearing and hearing loss. Through recent advances, we have begun to understand the …