A new paradigm in transplant immunology: At the crossroad of synthetic biology and biomaterials
Z Zhang, L Ding, X Zuo, H Feng, Q Xia - Med, 2023 - cell.com
Solid organ transplant (SOT) recipients require meticulously tailored immunosuppressive
regimens to minimize graft loss and mortality. Traditional approaches focus on inhibiting …
regimens to minimize graft loss and mortality. Traditional approaches focus on inhibiting …
Transplantation immune responses: Biology, challenges, and opportunities using biomaterials
The organs or cells transplantation is well-established in clinics. However, despite the
increasing success rates and the broadening of various transplantation techniques, a key …
increasing success rates and the broadening of various transplantation techniques, a key …
Unlocking Transplant Tolerance with Biomaterials
JPA Pham, MM Coronel - Advanced Healthcare Materials, 2024 - Wiley Online Library
For patients suffering from organ failure due to injury or autoimmune disease, allogeneic
organ transplantation with chronic immunosuppression is considered the gold standard in …
organ transplantation with chronic immunosuppression is considered the gold standard in …
[HTML][HTML] Emerging strategies to bypass transplant rejection via biomaterial-assisted immunoengineering: Insights from islets and beyond
S Abbaszadeh, V Nosrati-Siahmazgi, K Musaie… - Advanced Drug Delivery …, 2023 - Elsevier
Novel transplantation techniques are currently under development to preserve the function
of impaired tissues or organs. While current technologies can enhance the survival of …
of impaired tissues or organs. While current technologies can enhance the survival of …
Biomaterials: foreign bodies or tuners for the immune response?
E Mariani, G Lisignoli, RM Borzì… - International journal of …, 2019 - mdpi.com
The perspectives of regenerative medicine are still severely hampered by the host response
to biomaterial implantation, despite the robustness of technologies that hold the promise to …
to biomaterial implantation, despite the robustness of technologies that hold the promise to …
Biomaterial-based approaches to engineering immune tolerance
AE Emerson, EM Slaby, SC Hiremath… - Biomaterials Science, 2020 - pubs.rsc.org
The development of biomaterial-based therapeutics to induce immune tolerance holds great
promise for the treatment of autoimmune diseases, allergy, and graft rejection in …
promise for the treatment of autoimmune diseases, allergy, and graft rejection in …
Recent advances in biomaterial-boosted adoptive cell therapy
Adoptive immunotherapies based on the transfer of functional immune cells hold great
promise in treating a wide range of malignant diseases, especially cancers, autoimmune …
promise in treating a wide range of malignant diseases, especially cancers, autoimmune …
Engineering strategies for allogeneic solid tissue acceptance
Advances in allogeneic transplantation of solid organs and tissues depend on our
understanding of mechanisms that mediate the prevention of graft rejection. For the past …
understanding of mechanisms that mediate the prevention of graft rejection. For the past …
Engineering immune tolerance with biomaterials
Autoimmune diseases, rejection of transplanted organs and grafts, chronic inflammatory
diseases, and immune‐mediated rejection of biologic drugs impact a large number of …
diseases, and immune‐mediated rejection of biologic drugs impact a large number of …
Tissue‐Targeted Drug Delivery Strategies to Promote Antigen‐Specific Immune Tolerance
Y Rui, HB Eppler, AA Yanes… - Advanced healthcare …, 2023 - Wiley Online Library
During autoimmunity or organ transplant rejection, the immune system attacks host or
transplanted tissue, causing debilitating inflammation for millions of patients. There is no …
transplanted tissue, causing debilitating inflammation for millions of patients. There is no …