Electroacupuncture mediates extracellular signal-regulated kinase 1/2 pathways in the spinal cord of rats with inflammatory pain
JQ Fang, JF Fang, Y Liang, JY Du - BMC Complementary and Alternative …, 2014 - Springer
Background Activation of extracellular signal-regulated kinase1/2 (ERK1/2) in dorsal horn of
the spinal cord by peripheral inflammation is contributed to inflammatory pain …
the spinal cord by peripheral inflammation is contributed to inflammatory pain …
Electroacupuncture attenuates mechanical allodynia by suppressing the spinal JNK1/2 pathway in a rat model of inflammatory pain
JY Du, JQ Fang, Y Liang, JF Fang - Brain Research Bulletin, 2014 - Elsevier
Background Electroacupuncture (EA) has a substantial analgesic effect on inflammatory
pain induced by complete Freund's adjuvant (CFA). The activation of the c-Jun N-terminal …
pain induced by complete Freund's adjuvant (CFA). The activation of the c-Jun N-terminal …
Intervention of electroacupuncture on spinal p38 MAPK/ATF-2/VR-1 pathway in treating inflammatory pain induced by CFA in rats
JQ Fang, JY Du, Y Liang, JF Fang - Molecular Pain, 2013 - journals.sagepub.com
Background Previous studies have demonstrated that p38 MAPK signal transduction
pathway plays an important role in the development and maintenance of inflammatory pain …
pathway plays an important role in the development and maintenance of inflammatory pain …
Inhibition of chemokine CX3CL1 in spinal cord mediates the electroacupuncture-induced suppression of inflammatory pain
Y Li, Z Fang, N Gu, F Bai, Y Ma, H Dong… - Journal of pain …, 2019 - Taylor & Francis
Purpose Chemokine CX3CL1 and its receptor CX3CR1 in the lumbar spinal cord play
crucial roles in pain processing. Electroacupuncture (EA) is recognized as an alternative …
crucial roles in pain processing. Electroacupuncture (EA) is recognized as an alternative …
Effect of repeated electroacupuncture intervention on hippocampal ERK and p38MAPK signaling in neuropathic pain rats
J Wang, S Chen, Y Gao, L Qiao… - Evidence‐Based …, 2015 - Wiley Online Library
Results of our past studies showed that hippocampal muscarinic acetylcholine receptor
(mAChR)‐1 mRNA and differentially expressed proteins participating in MAPK signaling …
(mAChR)‐1 mRNA and differentially expressed proteins participating in MAPK signaling …
Electroacupuncture relieves pain and attenuates inflammation progression through inducing IL-10 production in CFA-induced mice
M Yu, R Wei, T Zhang, J Wang, Y Cheng, F Qin, S Fu… - Inflammation, 2020 - Springer
The therapeutic effect of electroacupuncture (EA) on inflammatory pain has been well
recognized clinically, but the mechanism is unclear. Interleukin-10 (IL-10), which is …
recognized clinically, but the mechanism is unclear. Interleukin-10 (IL-10), which is …
Electroacupuncture alleviates the transition from acute to chronic pain through the p38 MAPK/TNF-α signalling pathway in the spinal dorsal horn
Y Jin, J Zhou, F Xu, Z Ren, J Hu… - Acupuncture in …, 2021 - journals.sagepub.com
Background: Hyperalgesic priming (HP) is a model of the transition from acute to chronic
pain. Electroacupuncture (EA) could inhibit pain development through the peripheral dorsal …
pain. Electroacupuncture (EA) could inhibit pain development through the peripheral dorsal …
Electroacupuncture attenuates spinal nerve ligation-induced microglial activation mediated by p38 mitogen-activated protein kinase
Y Liang, J Du, Y Qiu, J Fang, J Liu, J Fang - Chinese journal of integrative …, 2016 - Springer
Objective To investigate whether analgesic effect of electroacupuncture (EA) is affected by
p38 mitogen-activated protein kinase (p38 MAPK) on microglia. Methods There were two …
p38 mitogen-activated protein kinase (p38 MAPK) on microglia. Methods There were two …
Regulation of Neurotrophin‐3 and Interleukin‐1β and Inhibition of Spinal Glial Activation Contribute to the Analgesic Effect of Electroacupuncture in Chronic …
W Tu, W Wang, H Xi, R He, L Gao… - … and Alternative Medicine, 2015 - Wiley Online Library
Growing evidence indicates that neurotrophin‐3, interleukin‐1β, and spinal glia are involved
in neuropathic pain derived from dorsal root ganglia to spinal cord. Electroacupuncture is …
in neuropathic pain derived from dorsal root ganglia to spinal cord. Electroacupuncture is …
Electroacupuncture ameliorates mechanical hypersensitivity by down-regulating spinal Janus kinase 2/signal transducer and activation of transcription 3 and …
Y Wang, Y Xia, M Xue, Q Jiang… - Acupuncture in …, 2021 - journals.sagepub.com
Background: Evidence shows that the Janus kinase 2 (JAK2)/signal transducer and activator
of transcription 3 (STAT3) signaling pathway participates in the pathogenesis of neuropathic …
of transcription 3 (STAT3) signaling pathway participates in the pathogenesis of neuropathic …
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- inflammatory pain chemokine cx3cl1
- inflammatory pain p38 mapk
- chronic pain signalling pathway
- chemokine cx3cl1 spinal cord
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- inflammatory pain intervention of electroacupuncture