Prospects for anti-biofilm pharmaceuticals

PS Stewart - Pharmaceuticals, 2015 - mdpi.com
This commentary highlights several avenues currently being pursued in research labs to the
development of new anti-biofilm pharmaceuticals. There is a real need for alternative …

Development of antibiofilm therapeutics strategies to overcome antimicrobial drug resistance

S Nadar, T Khan, SG Patching, A Omri - Microorganisms, 2022 - mdpi.com
A biofilm is a community of stable microorganisms encapsulated in an extracellular matrix
produced by themselves. Many types of microorganisms that are found on living hosts or in …

New antibiotic agents and approaches to treat biofilm-associated infections

AS Lynch, D Abbanat - Expert opinion on therapeutic patents, 2010 - Taylor & Francis
Importance of the field: Current antibiotics have classically been developed to treat
infections involving planktonic bacterial populations in acute infection settings and are …

Novel approaches to combat bacterial biofilms

C Beloin, S Renard, JM Ghigo, D Lebeaux - Current opinion in …, 2014 - Elsevier
Highlights•Currently used antibiotics were developed to target planktonic bacteria.•Recent
discoveries on biofilm properties led to promising anti-biofilm strategies.•Biofilm inhibition …

Agents that inhibit bacterial biofilm formation

N Rabin, Y Zheng, C Opoku-Temeng, Y Du… - Future medicinal …, 2015 - Taylor & Francis
In the biofilm form, bacteria are more resistant to various antimicrobial treatments. Bacteria in
a biofilm can also survive harsh conditions and withstand the host's immune system …

[图书][B] Antibiofilm agents: from diagnosis to treatment and prevention

KP Rumbaugh, I Ahmad - 2014 - books.google.com
This book provides a survey of recent advances in the development of antibiofilm agents for
clinical and environmental applications. The fact that microbes exist in structured …

Novel treatment dynamics for biofilm-related infections

JL Del Pozo - Expert Review of Anti-infective Therapy, 2021 - Taylor & Francis
Introduction: As a result of progress in medical care, a huge number of medical devices are
used in the treatment of human diseases. In turn, biofilm-related infection has become a …

Resolving biofilm infections: current therapy and drug discovery strategies

MV Ranall, MS Butler, MA Blaskovich… - Current drug …, 2012 - ingentaconnect.com
Biofilms formed by pathogenic bacteria present a serious threat to human health as the
efficacy of standard antibiotic therapeutic regimens is compromised by reduced microbial …

Combination therapies for biofilm inhibition and eradication: a comparative review of laboratory and preclinical studies

S Hawas, AD Verderosa, M Totsika - Frontiers in cellular and infection …, 2022 - frontiersin.org
Microbial biofilms are becoming increasingly difficult to treat in the medical setting due to
their intrinsic resistance to antibiotics. To combat this, several biofilm dispersal agents are …

[HTML][HTML] How well are we translating biofilm research from bench-side to bedside?

KP Rumbaugh - Biofilm, 2020 - Elsevier
Biofilms are responsible for more than 80% of all chronic infections and represent an
enormous medical challenge. In order to meet this challenge, translation research on anti …