Behavioral and biochemical effects of alcohol withdrawal in female C3H/HeNRj and C57BL/6JRj mice

S Tonetto, P Weikop, T Brudek… - Frontiers in Behavioral …, 2023 - frontiersin.org
Background Alcohol use disorder (AUD) is a major problem of our society and is often
characterized and worsened by relapse. Prolonged alcohol exposure leads to numerous …

Sex and context differences in the effects of trauma on comorbid alcohol use and post‐traumatic stress phenotypes in actively drinking rats

D Kirson, MQ Steinman, SA Wolfe… - Journal of …, 2021 - Wiley Online Library
Alcohol use disorder (AUD) and affective disorders are frequently comorbid and share
underlying mechanisms that could be targets for comprehensive treatment. Post‐traumatic …

Sub-dimensions of alcohol use disorder in alcohol preferring and non-preferring rats, a comparative study

A Domi, S Stopponi, E Domi, R Ciccocioppo… - Frontiers in Behavioral …, 2019 - frontiersin.org
Recent animal models of alcohol use disorder (AUD) are centered in capturing individual
vulnerability differences in disease progression. Here, we used genetically selected …

Negative affect and excessive alcohol intake incubate during protracted withdrawal from binge-drinking in adolescent, but not adult, mice

KM Lee, MA Coehlo, NR Solton… - Frontiers in …, 2017 - frontiersin.org
Binge-drinking is common in underage alcohol users, yet we know little regarding the
biopsychological impact of binge-drinking during early periods of development. Prior work …

Animal models of alcohol use disorder and the brain: From casual drinking to dependence.

NA Crowley, NC Dao, SN Magee… - Translational Issues …, 2019 - psycnet.apa.org
Alcohol use disorder (AUD) is a chronically relapsing disorder, characterized by a shift from
casual to compulsive intake of alcohol that is driven by changes in multiple regions …

Advances in behavioral animal models of alcohol use disorder

K Goltseker, FW Hopf, S Barak - Alcohol, 2019 - Elsevier
Alcohol use disorder (AUD) is a multifaceted neuropsychiatric disease that combines
behavioral, psychosocial, and neurobiological aspects. Over the previous decade, animal …

Basal anxiety negatively correlates with vulnerability to ethanol‐induced behavioral sensitization in DBA/2J mice: modulation by Diazepam

B Botia, R Legastelois, H Houchi… - Alcoholism: Clinical …, 2015 - Wiley Online Library
Background Anxiety disorders predispose individuals to the development of alcohol
dependence in humans. Surprisingly, whether anxiety is a trait influencing the development …

Sex differences in binge alcohol drinking and the behavioral consequences of protracted abstinence in C57BL/6J mice

JK Rivera-Irizarry, LJ Zallar, OB Levine… - Biology of sex …, 2023 - Springer
Background Binge alcohol drinking is a risk factor linked to numerous disease states
including alcohol use disorder (AUD). While men binge drink more alcohol than women, this …

Affect-related behaviors in mice selectively bred for high and low voluntary alcohol consumption

A Can, NJ Grahame, TD Gould - Behavior genetics, 2012 - Springer
There is considerable evidence for the existence of comorbidity between alcohol-use
disorders and depression in humans. One strategy to elucidate hereditary factors affecting …

Assessment of depression-like behavior and anhedonia after repeated cycles of binge-like ethanol drinking in male C57BL/6J mice

JJ Olney, SA Marshall, TE Thiele - Pharmacology Biochemistry and …, 2018 - Elsevier
Psychological depression is frequently linked to alcohol abuse and even serves as key
indicators of an alcohol use disorder (AUD). This relationship is supported by preclinical …