There has been intense research into the role nitric oxide (NO) plays in physiological and
pathological mechanisms and its clinical significance in respiratory medicine. Elevated …

With more than 600 publications, exhaled nitric oxide (NO) has been extensively
investigated as a noninvasive marker of airway inflammation in a research setting. This …

Nitric oxide (NO) is synthesized from the amino acid arginine by enzymes called nitric oxide
synthases. NO has an important physiologic role in the regulation of vascular tone, response …

The analysis of biomarkers in exhaled breath constituents has recently become of great
interest in the diagnosis, treatment and monitoring of many respiratory conditions. Of …

Background Nitric oxide (NO) plays an important role as an inflammatory mediator in the
airways. Though direct measurement of endogenous NO has been difficult in humans, we …

Much interest is now being focused on measurements of nitric oxide (NO) in exhaled air. In
healthy subjects exhaled NO seems to originate mainly in the nasal airways, whereas the …

Although originally described as endothelial-derived relaxing factor important in arterial
tone, nitric oxide (NO) is now considered an important biomarker for respiratory disease. 1, 2 …

There has been intense research into the role nitric oxide (NO) plays in physiologic and
pathologic mechanisms. The presence of NO in exhaled breath and the high concentrations …

BACKGROUND Patients with difficult asthma suffer chronic moderate to severe persistent
asthma symptoms despite high doses of inhaled and oral corticosteroid therapy. These …

Nitric oxide (NO), an evanescent atmospheric gas, has recently been discovered to be an
important biological mediator in animals and humans. Nitric oxide plays a key role within the …