Phosphate handling in CKD-MBD from stage 3 to dialysis and the three strengths of lanthanum carbonate
M Cozzolino, E Bruschetta, D Cusi… - Expert opinion on …, 2012 - Taylor & Francis
Introduction: High phosphate levels are associated with unfavorable outcomes in ESRD.
Recent data suggested that phosphate levels within the normal range are equally …
Recent data suggested that phosphate levels within the normal range are equally …
Overview of the FGF23-Klotho axis
M Kuro-o - Pediatric nephrology, 2010 - Springer
Recent studies have identified a novel bone− kidney endocrine axis that maintains
phosphate homeostasis. When phosphate is in excess, fibroblast growth factor-23 (FGF23) …
phosphate homeostasis. When phosphate is in excess, fibroblast growth factor-23 (FGF23) …
Jury still out on whether FGF23 is a direct contributor, a useful biomarker, or neither
H Komaba, M Fukagawa - Kidney International, 2021 - kidney-international.org
Fibroblast growth factor 23 (FGF23) is an endocrine hormone that is mainly produced by
osteocytes. In patients with chronic kidney disease (CKD), circulating FGF23 levels increase …
osteocytes. In patients with chronic kidney disease (CKD), circulating FGF23 levels increase …
Novel insights into mechanisms of intestinal phosphate absorption in patients with chronic kidney disease
K Kritmetapak, R Kumar - Journal of the American Society of …, 2021 - journals.lww.com
CKD associates with phosphate retention, contributing to an increased risk of secondary
hyperparathyroidism, vascular calcification, and cardiovascular mortality …
hyperparathyroidism, vascular calcification, and cardiovascular mortality …
Disorders of phosphorus homeostasis
R Lee, TJ Weber - Current Opinion in Endocrinology, Diabetes …, 2010 - journals.lww.com
These findings in total provide fertile ground for investigations into the cause and treatment
of abnormal skeletal and extraskeletal calcification in patients with inherited …
of abnormal skeletal and extraskeletal calcification in patients with inherited …
The phosphorus–proteinuria interaction in chronic kidney disease
D Fouque - Nephrology Dialysis Transplantation, 2013 - academic.oup.com
Phosphorus is a key mineral for normal cell function, enzyme activity, energy metabolism
and growth, and having too little or too much phosphorus will reduce lifespan. Abnormal …
and growth, and having too little or too much phosphorus will reduce lifespan. Abnormal …
Assessment of tubular reabsorption of phosphate as a surrogate marker for phosphate regulation in chronic kidney disease
YA Hong, JH Lim, MY Kim, Y Kim, KS Yang… - Clinical and …, 2015 - Springer
Abstract Background/Aims Fibroblast growth factor 23 (FGF23) and soluble α-Klotho are
emerging potential biomarkers of phosphorus and vitamin D metabolism which change in …
emerging potential biomarkers of phosphorus and vitamin D metabolism which change in …
Inherited non-FGF23-mediated phosphaturic disorders: a kidney-centric review
E Walker, W Hayes, D Bockenhauer - Best Practice & Research Clinical …, 2023 - Elsevier
Phosphate is freely filtered by the glomerulus and reabsorbed exclusively in the proximal
tubule by two key transporters, NaPiIIA and NaPiIIC, encoded by SLC34A1 and SLC34A3 …
tubule by two key transporters, NaPiIIA and NaPiIIC, encoded by SLC34A1 and SLC34A3 …
Small steps towards the potential of 'preventive'treatment of early phosphate loading in chronic kidney disease patients
J Bover, M Cozzolino - Clinical Kidney Journal, 2019 - academic.oup.com
Few clinical studies have investigated the value of phosphate (P)-lowering therapies in early
chronic kidney disease (CKD) patients in whom hyperphosphataemia has not yet clearly …
chronic kidney disease (CKD) patients in whom hyperphosphataemia has not yet clearly …