Abstract Fibroblast growth factor 23 (FGF23) is a phosphaturic and vitamin D‐regulatory
hormone of putative bone origin that is elevated in patients with chronic kidney disease …

The molecular identification and characterization of genetic defects leading to a number of
rare inherited or acquired disorders affecting phosphate homeostasis has added …

The kidneys, through proximal tubular active uptake or pass-through of filtered phosphorus,
regulate phosphorus homeostasis in healthy individuals. Hormones and factors that …

The CKD mineral bone disorder is a new term coined to describe the multiorgan system
failure that is a major component of the excess cardiovascular mortality and morbidity …

Chronic kidney disease (CKD) is associated with distinct alterations in mineral metabolism
in children and adults resulting in multiple organ dysfunctions. Children with advanced CKD …

Disturbances in phosphate homeostasis are common in patients with chronic kidney
disease. As kidney function declines, circulating concentrations of phosphate and the …

High concentrations of extracellular phosphate are toxic to cells. Impaired urinary phosphate
excretion increases serum phosphate level and induces a premature-ageing phenotype …

Fibroblast growth factor 23 and phosphate homeostasis : Current Opinion in Nephrology and
Hypertension Fibroblast growth factor 23 and phosphate homeostasis : Current Opinion in …

Background: Phosphate (Pi) overload may lead to adverse outcomes in CKD, but
challenges persist in evaluating Pi overload because serum Pi levels remain in the normal …

In chronic kidney disease (CKD), high serum phosphate concentration is associated with
cardiovascular disease and deterioration in renal function. In early CKD, the serum …