Spatiotemporal analysis of DNA integration during natural transformation reveals a mode of nongenetic inheritance in bacteria

AB Dalia, TN Dalia - Cell, 2019 - cell.com
Natural transformation (NT) is a major mechanism of horizontal gene transfer in microbial
species that promotes the spread of antibiotic-resistance determinants and virulence factors …

Distributive conjugal transfer: new insights into horizontal gene transfer and genetic exchange in mycobacteria

KM Derbyshire, TA Gray - Molecular Genetics of Mycobacteria, 2014 - Wiley Online Library
Eukaryotes use meiotic recombination to blend parental genomes and generate genome‐
wide variation between progeny. By contrast, bacteria divide asexually to generate two …

Horizontal gene transfer and ecosystem function dynamics

M van de Guchte - Trends in microbiology, 2017 - cell.com
Horizontal gene transfer can provide bacteria with new functions that confer an important
competitive advantage, and is therefore likely to affect the dynamics of bacterial ecosystems …

Horizontal gene transfer in evolution: facts and challenges

L Boto - Proceedings of the Royal Society B: Biological …, 2010 - royalsocietypublishing.org
The contribution of horizontal gene transfer to evolution has been controversial since it was
suggested to be a force driving evolution in the microbial world. In this paper, I review the …

Genetic exchange in natural microbial communities

DA Veal, HW Stokes, G Daggard - Advances in microbial ecology, 1993 - Springer
Genetic exchange between bacteria was first observed over 60 years ago (Griffith, 1928). In
recent years, considerable advances have been made in the understanding of the molecular …

Dimensions of horizontal gene transfer in eukaryotic microbial pathogens

E Gluck-Thaler, JC Slot - PLoS pathogens, 2015 - journals.plos.org
Comparative genomic studies of microorganisms have disrupted the paradigm of vertical
inheritance with modification. First in bacteria, and more recently in microscopic and even …

Genetic variation: molecular mechanisms and impact on microbial evolution

W Arber - FEMS microbiology reviews, 2000 - academic.oup.com
On the basis of established knowledge of microbial genetics one can distinguish three major
natural strategies in the spontaneous generation of genetic variations in bacteria. These …

Horizontal gene transfer in eukaryotes: not if, but how much?

J Van Etten, D Bhattacharya - Trends in Genetics, 2020 - cell.com
Horizontal gene transfer (HGT), the movement of genetic material across branches of the
tree of life, is well established in prokaryotes and uncontroversial. This is explained in part …

[HTML][HTML] Natural genetic transformation: prevalence, mechanisms and function

O Johnsborg, V Eldholm, LS Håvarstein - Research in microbiology, 2007 - Elsevier
Studies show that gene acquisition through natural transformation has contributed
significantly to the adaptation and ecological diversification of several bacterial species …

Exploring the costs of horizontal gene transfer

DA Baltrus - Trends in ecology & evolution, 2013 - cell.com
Horizontal gene transfer (HGT) is one of the most important evolutionary forces within
microbial populations. Although evidence for beneficial fitness effects of HGT is …