Objectives HLA-DRB1 is associated with an increased risk of cardiovascular disease in
patients with rheumatoid arthritis (RA). This study aimed to determine the effect of HLA …

Background: Human leukocyte antigen (HLA) complex is a gene family involved in antigen
presentation associated with protection or susceptibility to inflammatory, infectious and …

The pathogenesis of coronary artery disease (CAD) is closely associated with inflammation,
in which human leukocyte antigens (HLA), especially HLA-DR molecules, play important …

Objective To examine the role of the variants of the PTPN22 and HLA–DRB1 genes as
predictors of mortality in inflammatory polyarthritis (IP) and rheumatoid arthritis (RA) …

Objective Cardiovascular (CV) disease is the most common cause of mortality in patients
with rheumatoid arthritis (RA). We assessed the contribution of epidemiologic features …

We read with great interest the recent report by Farragher et al, describing a study in which
the authors confirmed the association of HLA–DRB1 shared epitope (SE) alleles with …

Background Rheumatoid Arthritis (RA) is an autoimmune disease characterized by chronic
inflammation of the joints that affects approximately 1% of the population worldwide. The …

Cardiovascular disease is the commonest cause of premature mortality in rheumatoid
arthritis (RA) patients. Vascular endothelial injury is the primary event in atherosclerosis. It …

Higher cardiovascular morbidity in patients with a wide range of autoimmune diseases
highlights the importance of autoimmunity in promoting atherosclerosis. Our purpose was to …

Rheumatoid arthritis (RA) is an autoimmune disease causing chronic inflammation of the
joints. Multiple factors, including HLA-DRB1 gene variants, influence the susceptibility to RA …