The mechanisms of reperfusion damage following focal cerebral ischemia are not known in
detail. Recent results, however, strongly suggest that reactive oxygen species (ROS) …

Recent results have demonstrated that the spin trapping agent N-tert-butyl-alpha-
phenylnitrone (PBN) reduces infarct size due to middle cerebral artery occlusion (MCAO) …

The present experiments were undertaken to explore the mechanisms of secondary brain
damage in focal ischemia of long duration (2 h), followed by recirculation. Recirculation has …

Previously, we described cellular changes following Permanent Middle Cerebral Artery
Occlusion (PMCAO) in spontaneously hypertensive rats. Ischemic changes following …

The objective of this article is to amalgamate previous results into a speculative synthesis
that sheds light on the causes of secondary brain damage following either global/forebrain …

Abstract RECENT EVIDENCE INDICATES that thrombolysis may be an effective therapy for
the treatment of acute ischemic stroke. However, the reperfusion of ischemic brain comes …

Introduction Restoration of blood flow following ischemic stroke can be achieved by means
of thrombolysis or mechanical recanalization. However, for some patients, reperfusion may …

Cardiopulmonary resuscitation for victims of cardiac arrest, both within and outside of the
hospital, succeeds in restoring spontaneous circulation in about 70,000 patients a year in …

Brain ischemia and reperfusion engage multiple independently-fatal terminal pathways
involving loss of membrane integrity in partitioning ions, progressive proteolysis, and …

Recent works in the area of stroke and brain ischemia has demonstrated the significance of
the inflammatory response accompanying necrotic brain injury. Acutely, this response …