Rationale: Inhomogeneous hypoxic pulmonary vasoconstriction causing regional
overperfusion and high capillary pressure is postulated for explaining how high pulmonary …

High altitude pulmonary edema (HAPE) is a rapidly reversible hydrostatic edema that occurs
in individuals who travel to high altitude. The difficulties associated with making physiologic …

We hypothesized that some of the heterogeneity of pulmonary blood flow present in the
normal human lung in normoxia is due to hypoxic pulmonary vasoconstriction (HPV). If so …

Uneven hypoxic pulmonary vasoconstriction has been proposed to expose parts of the
pulmonary capillary bed to high pressure and vascular injury in high-altitude pulmonary …

Background—Pulmonary hypertension has been suggested to play an important role in
development of high-altitude pulmonary edema (HAPE), and individual susceptibility has …

Hypoxic pulmonary vasoconstriction is the elegant theory put forward more than six decades
ago to explain regional variations in perfusion within the lung in certain animal species in …

RATIONALE AND OBJECTIVES: Hypoxic pulmonary vasoconstriction (HPV) is a
homeostatic mechanism causing pulmonary arterial constriction in response to local …

High altitude pulmonary edema (HAPE) is a non-cardiogenic pulmonary edema that can
occur in healthy individuals who ascend rapidly to altitudes above 3000–4000m. Excessive …

Rationale: High-altitude pulmonary edema (HAPE) is characterized by excessive pulmonary
vasoconstriction and is associated with decreased concentrations of nitric oxide (NO) in the …

High-altitude pulmonary edema (HAPE) develops in rapidly ascending nonacclimatized
healthy individuals at altitudes above 3,000 m. An excessive rise in pulmonary artery …