Obesity, inflammation, and postmenopausal breast cancer: therapeutic implications
Breast cancer is the female malignant neoplasia with the highest incidence in the
industrialized world. Although early diagnosis has contributed to therapeutic success, breast …
industrialized world. Although early diagnosis has contributed to therapeutic success, breast …
Metabolic pathways in obesity-related breast cancer
KA Brown - Nature Reviews Endocrinology, 2021 - nature.com
This Review focuses on the mechanistic evidence for a link between obesity, dysregulated
cellular metabolism and breast cancer. Strong evidence now links obesity with the …
cellular metabolism and breast cancer. Strong evidence now links obesity with the …
Obesity associated alterations in the biology of adipose stem cells mediate enhanced tumorigenesis by estrogen dependent pathways
Introduction Obesity has been associated with increased incidence and mortality of breast
cancer. While the precise correlation between obesity and breast cancer remains to be …
cancer. While the precise correlation between obesity and breast cancer remains to be …
Obesity and inflammation: new insights into breast cancer development and progression
NM Iyengar, CA Hudis, AJ Dannenberg - American Society of Clinical …, 2013 - ascopubs.org
The importance of inflammation in promoting carcinogenesis and tumor progression is well
recognized. Chronic inflammation caused by a variety of infectious agents can lead to the …
recognized. Chronic inflammation caused by a variety of infectious agents can lead to the …
Obesity and breast cancer: molecular interconnections and potential clinical applications
V Simone, M D'avenia, A Argentiero, C Felici… - The …, 2016 - academic.oup.com
Obesity is an important risk factor for breast cancer (BC) in postmenopausal women;
interlinked molecular mechanisms might be involved in the pathogenesis. Increased levels …
interlinked molecular mechanisms might be involved in the pathogenesis. Increased levels …
Updated clinical evidence on the role of adipokines and breast cancer: a review
Simple Summary Breast cancer is currently one of the most common types of cancer and the
number one cause of cancer-related deaths in women worldwide. Despite significant …
number one cause of cancer-related deaths in women worldwide. Despite significant …
The impact of obesity and adipokines on breast and gynecologic malignancies
S Tewari, R Vargas, O Reizes - … of the New York Academy of …, 2022 - Wiley Online Library
The link between obesity and multiple disease comorbidities is well established. In 2003,
Calle and colleagues presented the relationship between obesity and several cancer types …
Calle and colleagues presented the relationship between obesity and several cancer types …
Multifaceted breast cancer: the molecular connection with obesity
A Feola, S Ricci, S Kouidhi, A Rizzo… - Journal of Cellular …, 2017 - Wiley Online Library
Obesity is characterized by a disruption in energy balance regulation that results in an
excess accumulation of body fat. Its increasing prevalence poses a major public health …
excess accumulation of body fat. Its increasing prevalence poses a major public health …
The effects of adipocytes on the regulation of breast cancer in the tumor microenvironment: an update
DT Chu, T Nguyen Thi Phuong, NLB Tien, DK Tran… - Cells, 2019 - mdpi.com
Obesity is a global pandemic and it is well evident that obesity is associated with the
development of many disorders including many cancer types. Breast cancer is one of that …
development of many disorders including many cancer types. Breast cancer is one of that …
Obesity and breast cancer: current insights on the role of fatty acids and lipid metabolism in promoting breast cancer growth and progression
C Blücher, SC Stadler - Frontiers in endocrinology, 2017 - frontiersin.org
Obesity and excess accumulation of adipose tissue are known risk factors for several types
of cancer, including breast cancer. With the incidence of obesity constantly rising worldwide …
of cancer, including breast cancer. With the incidence of obesity constantly rising worldwide …