Over the last 8 years the Psychiatric Genomics Consortium (PGC; http://pgc. unc. edu) has
fundamentally changed the landscape for psychiatric genetics research. This has been …

Genetics constitute a crucial risk factor to schizophrenia. In the last decade, molecular
genetic research has produced novel findings, infusing optimism about discovering the …

In the past 20 years, association studies of schizophrenia have evolved from analyses in
lesser than 100 subjects of one or two markers in candidate genes to systematic analyses of …

The range of genetic variation with potential clinical implications in schizophrenia, beyond
rare copy number variants (CNVs), remains uncertain. We therefore analyzed genome …

Schizophrenia is an idiopathic mental disorder with a heritable component and a substantial
public health impact. We conducted a multi-stage genome-wide association study (GWAS) …

Genetically, schizophrenia is a complex disease whose pathogenesis is likely governed by
a number of different risk factors. While substantial efforts have been made to identify the …

Schizophrenia is a debilitating psychiatric condition often associated with poor quality of life
and decreased life expectancy. Lack of progress in improving treatment outcomes has been …

Objectives: Schizophrenia is a severe psychiatric disease affecting about 1% of the general
population. The relative contribution of genetic factors has been estimated to be up to 80 …

Schizophrenia is a common, chronic and debilitating neuropsychiatric syndrome affecting
tens of millions of individuals worldwide. While rare genetic variants play a role in the …

There has been substantial progress in understanding the genetics of schizophrenia over
the past 15 years. This has revealed a highly polygenic condition with the majority of the …