Objective Nitidine chloride (NC), a natural small molecular compound from traditional
Chinese herbal medicine zanthoxylum nitidum, has been shown to exhibit anti-tumor effect …

Tumor necrosis factor-α (TNF-α) is a pro-inflammatory cytokine produced by monocytes/
macrophage that plays a pathological role in rheumatoid arthritis (RA). In this study, we …

Synovial inflammation plays a central role in joint destruction and pain in osteoarthritis (OA).
The NF-κB pathway plays an important role in the inflammatory process and is activated in …

Background Effective treatment methods for rheumatoid arthritis (RA) are still lacking.
Previous studies have shown that icariin exerts a significant therapeutic effect on RA; …

Our study aimed to determine the effects of sodium tanshinone IIA sulfonate (STS) on
proliferation, migration, invasion, and inflammation in rheumatoid arthritis human fibroblast …

Triptolide, a primary active ingredient extracted from a traditional Chinese herb, Tripterygium
wilfordii Hook F, has been demonstrated to have a positive therapeutic effect on patients …

Background Rheumatoid arthritis (RA) is a systemic disease characterized by chronic
synovial infiltration and proliferation, cartilage destruction, and joint injury. Ginkgolide B (GB) …

Rheumatoid arthritis (RA) is a chronic and progressive autoimmune disease in which
activated RA fibroblast-1ike synoviocytes (RA-FLSs) are one of the main factors responsible …

Rheumatoid arthritis (RA) is an autoimmune disease in which cytokine such as tumor
necrosis factor‐α (TNF‐α), activate synovial fibroblast (FLS) that results in inflammation and …

Objectives This study evaluated the anti-inflammatory effect of niclosamide in tumor necrosis
factor (TNF)-α-stimulated human rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLS) …