The vascular endothelial growth factor (VEGF) family binds multiple endothelial cell surface
receptors. Our goal is to build comprehensive models of these interactions for the purpose of …

The vascular endothelial growth factor receptors (VEGFR) play a significant role in
angiogenesis, the formation of new blood vessels from existing vasculature. Systems …

Vascular endothelial growth factor (VEGF) is a potent cytokine involved in the induction of
neovascularization. Secreted as a cysteine-linked dimer, it has two binding sites at opposite …

Most physiological processes are subjected to molecular regulation by growth factors, which
are secreted proteins that activate chemical signal transduction pathways through binding of …

Several cytokine families have roles in the development, maintenance, and remodeling of
the microcirculation. Of these, the vascular endothelial growth factor (VEGF) family is one of …

Vascular endothelial growth factor (VEGF) is a key regulator of angiogenesis–the growth of
new microvessels from existing microvasculature. Angiogenesis is a complex process …

The splice isoforms of vascular endothelial growth A (VEGF) each have different affinities for
the extracellular matrix (ECM) and the coreceptor NRP1, which leads to distinct vascular …

Vascular endothelial growth factor (VEGF) signal transduction through the cell surface
receptors VEGFR1 and VEGFR2 regulates angiogenesis—the growth of new capillaries …

Placental growth factor (PlGF) competes with vascular endothelial growth factor (VEGF) for
binding to VEGF receptor (VEGFR)-1 but does not bind VEGFR2. Experiments show that …

The vascular endothelial growth factor (VEGF) is believed to be the most important protein in
the regulation of the angiogenic cascade. Thus, exploring the structure and dynamical …