[HTML][HTML] Clinical signs, pathophysiology and management of skin toxicity during therapy with epidermal growth factor receptor inhibitors

S Segaert, E Van Cutsem - Annals of oncology, 2005 - Elsevier
The last few years, new therapies targeting the epidermal growth factor receptor (EGFR)
have shown their efficacy in the treatment of several types of cancer. Monoclonal antibodies …

Treatment of epidermal growth factor receptor antagonist-induced skin rash: results of a survey among German oncologists

JC Hassel, M Kripp, S Al-Batran… - Oncology Research and …, 2010 - karger.com
Background: Skin toxicities are frequent in patients receiving epidermal growth factor
receptor (EGFR) antagonists. Grading and management of these skin reactions are poorly …

Pan Canadian rash trial: a randomized phase III trial evaluating the impact of a prophylactic skin treatment regimen on epidermal growth factor receptor-tyrosine …

B Melosky, H Anderson, RL Burkes, Q Chu… - Journal of Clinical …, 2016 - ascopubs.org
Purpose Erlotinib is an epidermal growth factor receptor inhibitor approved for patients with
advanced non–small-cell lung cancer (NSCLC) whose epidermal growth factor receptor …

Evidence-based treatment options for the management of skin toxicities associated with epidermal growth factor receptor inhibitors

EH Tan, A Chan - Annals of Pharmacotherapy, 2009 - journals.sagepub.com
Objective: To compile evidence from randomized controlled trials, case series, and case
reports to identify the effectiveness of various therapeutic agents for the treatment and …

Common side effects of anti-EGFR therapy: acneform rash

R Sipples - Seminars in Oncology Nursing, 2006 - Elsevier
OBJECTIVES: To review the general toxicity profile of EGFR-targeted therapies and the
management of the most common side effect, skin toxicity. DATA SOURCES: Research …

Skin toxicities associated with epidermal growth factor receptor inhibitors

T Li, R Perez-Soler - Targeted oncology, 2009 - Springer
The use of epidermal growth factor receptor (EGFR) inhibitors in several epithelial tumors
has increased considerably in recent years. Currently, they are approved in non-small cell …

Impact and management of skin toxicity associated with anti-epidermal growth factor receptor therapy: survey results

SL Boone, A Rademaker, D Liu, C Pfeiffer, DJ Mauro… - Oncology, 2008 - karger.com
Biologic agents targeting the epidermal growth factor receptor (EGFR) have emerged as a
robust treatment option for various solid tumors. Despite lower systemic side effects than …

Clinical practice guidelines for the prevention and treatment of EGFR inhibitor-associated dermatologic toxicities

ME Lacouture, MJ Anadkat, RJ Bensadoun… - Supportive Care in …, 2011 - Springer
Background Epidermal growth factor receptor inhibitors (EGFRI) produce various
dermatologic side effects in the majority of patients, and guidelines are crucial for the …

Erlotinib induced skin rash spares skin in previous radiotherapy field.

SS Mitra, R Simcock - Journal of Clinical Oncology: Official Journal …, 2006 - europepmc.org
A comment on this article appears in" Radiation-induced prevention of erlotinib-induced skin
rash is transient: a new aspect toward the understanding of epidermal growth factor receptor …

EGFR inhibitors and cutaneous complications: a practical approach to management

LM Guggina, AW Choi, JN Choi - Oncology and Therapy, 2017 - Springer
Epidermal growth factor receptor inhibitors (EGFRIs) are increasingly being used for
malignancies of epithelial origin. Though these therapies are better tolerated than …