HIF (hypoxia-inducible factor)-3α is the third member of the HIF transcription factor family.
Whereas HIF-1α and-2α play critical roles in the cellular and systemic adaptation to hypoxia …

The hypoxia-inducible transcription factor (HIF) controls (in an oxygen-dependent manner)
the expression of a large number of genes whose products are involved in the response of …

The hypoxia-inducible transcription factors (HIFs) play a central role in the response of cells
to hypoxia. HIFs are αβ dimers, the human α subunit having three isoforms. HIF-3α is unique …

Hypoxia inducible factors (HIFs) are heterodimeric transcription factors that regulate a
number of adaptive responses to low oxygen tension. They are composed of α-and β …

ABSTRACT A universal response to changes in cellular oxygen tension is governed by a
family of heterodimeric transcription factors called hypoxia‐inducible factor (HIF). Tumor …

Hypoxia inducible factors (HIFs) are transcription factors, which are commonly expressed in
mammals, including humans. The HIFs consist of hypoxia-regulated α and oxygen …

The hypoxia-inducible factor (HIF) family has three distinct members in most vertebrates. All
three HIFs consist of a unique and oxygen-labile α-subunit and a common and stable β …

Hypoxia-inducible factors (HIFs) play key roles in the cellular response to hypoxia. It is
widely accepted that whereas HIF-1 and HIF-2 function as transcriptional activators, HIF-3 …

Hypoxia-inducible factor 1 (HIF-1) is a heterodimeric transcription factor that is critical for
hypoxic induction of a number of physiologically important genes. We present evidence that …

Abstract Hypoxia-inducible factor 1 (HIF-1) is the founding member of a family of
transcription factors that function as master regulators of oxygen homeostasis. HIF-1 is …