The binding interaction between erlotinib (ELTN) and calf thymus DNA (ct‐DNA) was
characterized with the help of multi‐spectroscopic approaches, viscosity measurement and …

A comprehensive investigation of tyrosine kinase inhibitor erlotinib (ERL) electrochemical
behavior and interaction with DNA was performed with the aim to clarify its redox …

The binding characteristics of calf thymus DNA (ct-DNA) with dasatinib (DSTN), a tyrosine
kinase inhibitor was assessed through multi-spectroscopic methodologies and viscosity …

The binding interaction of gefitinib with calf thymus DNA (ct-DNA) under the simulated
physiological pH condition was studied employing UV absorption, fluorescence, circular …

The study of the intermolecular binding interaction of small molecules with DNA can guide
the rational drug design with greater efficacy and improved or more selective activity. In the …

Epidermal growth factor receptor (EGFR) plays an important role in cell proliferation at non-
small cell lung cancer (NSCLC). Therefore, targeted therapy of cancer via this kind of …

Background: Interactions of drugs with DNA and proteins may modify their biological
activities and conformations, which effect transport and biological metabolism of drugs …

The investigation on the binding interaction mechanism of florfenicol with DNA in vitro was
reported via multi-spectroscopy measurements and molecular docking approach in the …

Lapatinib, a double-target receptor tyrosine kinase inhibitor, is an oral-targeted anticancer
drug developed by GlaxoSmithKline (GSK). It mainly acts on epidermal growth factor …

Fludarabine is a purine derivative, anti-neoplastic drug and is still being used in the
treatments of chronic lymphocytic leukemia, small lymphocytic lymphoma, acute myeloid …