[HTML][HTML] Bovine serum albumin binding study to erlotinib using surface plasmon resonance and molecular docking methods

P Taghipour, M Zakariazadeh, M Sharifi… - … of Photochemistry and …, 2018 - Elsevier
Bovine serum albumin (BSA) is the most abundant protein in the blood circulation and it is
commonly used for drug delivery in blood. Therefore, we aim to study BSA interaction with …

Exploring the binding interaction between herring sperm DNA and sunitinib: insights from spectroscopic and molecular docking approaches

JH Shi, DQ Pan, KL Zhou, YY Lou - Journal of Biomolecular …, 2019 - Taylor & Francis
Sunitinib (Figure 1) is a multi-targeted receptor tyrosine kinase (RTK) inhibitor (Lee &
Motzer, 2015), which has been widely used to treat renal cell carcinoma (RCC)(Wentink et …

In vitro exploration of interaction behavior between calf thymus DNA and fenhexamid with the help of multi-spectroscopic methods and molecular dynamics …

SB Kou, YY Lou, KL Zhou, BL Wang, ZY Lin… - Journal of Molecular …, 2019 - Elsevier
As an amide fungicide, fenhexamid has been extensively used to control botrytis and
sclerotinia as well as antagonize the resistant bacteria produced by other pesticides. But …

Increased DNA Binding Specificity for Antitumor Ecteinascidin 743 through Protein− DNA Interactions?

R García-Nieto, I Manzanares, C Cuevas… - Journal of medicinal …, 2000 - ACS Publications
Ecteinascidin 743 (ET743) is a marine natural product consisting of three linked
tetrahydroisoquinoline subunits and an active carbinolamine functional group (Figure 1) …

A spectroscopic study on the interaction between the anticancer drug erlotinib and human serum albumin

Z Ye, Y Ying, X Yang, Z Zheng, J Shi, Y Sun… - Journal of Inclusion …, 2014 - Springer
The interaction between erlotinib and human serum albumin (HSA) in simulated
physiological conditions was investigated by spectroscopic methods. The results revealed …

Multi-spectroscopic and molecular simulation methods of analysis to explore the mode of binding of Mebendazole drug with calf-thymus DNA

K Pavithra, RD Priyadharshini, KN Vennila… - … Acta Part A: Molecular …, 2023 - Elsevier
UV–vis, fluorescence, circular dichroism (CD) and 1 H NMR spectroscopic techniques have
been employed to explore the mode of binding of Mebendazole (MBZ) drug with calf thymus …

A phenanthroline-based erbium (III) complex: molecular docking, DNA/BSA-binding and biological evaluation

FF Albaqami, AS Sahib, KM Alharthy… - Journal of …, 2023 - Taylor & Francis
With the help of both theoretical as well as experimental research, in vitro binding research
with CT-DNA (calf thymus) and BSA (bovine serum albumin) were carefully examined to …

Thermodynamic investigation of the interaction between the [(η 6-p-cymene) Ru (benzaldehyde-N 4-phenylthiosemicarbazone) Cl] Cl anticancer drug and ctDNA …

S Huang, F Zhu, Q Xiao, Y Liang, Q Zhou, W Su - RSC Advances, 2015 - pubs.rsc.org
In this contribution, the interaction between the [(η6-p-cymene) Ru (benzaldehyde-N4-
phenylthiosemicarbazone) Cl] Cl anticancer drug and calf thymus DNA (ctDNA) was …

[HTML][HTML] Mutation induced conformational changes in genomic DNA from cancerous K562 cells influence drug-DNA binding modes

D Ghosh, SK Dey, C Saha - PLoS One, 2014 - journals.plos.org
Normal human genomic DNA (N-DNA) and mutated DNA (M-DNA) from K562 leukemic cells
show different thermodynamic properties and binding affinities on interaction with anticancer …

Interaction of indomethacin with calf thymus DNA: a multi-spectroscopic, thermodynamic and molecular modelling approach

MA Husain, HM Ishqi, T Sarwar, SU Rehman… - …, 2017 - pubs.rsc.org
Indomethacin belongs to the acetic acid derivative class of non-steroidal anti-inflammatory
drugs with diverse pharmacological and biological activities. Understanding the mechanism …