[HTML][HTML] Targeted Demethylation of the TGFβ1 mRNA Promotes Myoblast Proliferation via Activating the SMAD2 Signaling Pathway
K Deng, Z Liu, X Li, Z Zhang, Y Fan, Q Huang, Y Zhang… - Cells, 2023 - mdpi.com
Recent evidence suggested that N6-methyladenosine (m6A) methylation can determine
m6A-modified mRNA fate and play an important role in skeletal muscle development. It was …
m6A-modified mRNA fate and play an important role in skeletal muscle development. It was …
[HTML][HTML] FTO-mediated demethylation of GADD45B promotes myogenesis through the activation of p38 MAPK pathway
K Deng, Y Fan, Y Liang, Y Cai, G Zhang… - … Therapy-Nucleic Acids, 2021 - cell.com
N6-methyladenosine (m 6 A) modification plays a critical role in mammalian development.
However, the role of m 6 A in the skeletal muscle development remains largely unknown …
However, the role of m 6 A in the skeletal muscle development remains largely unknown …
[HTML][HTML] Dynamic m6A mRNA Methylation Reveals the Role of METTL3/14-m6A-MNK2-ERK Signaling Axis in Skeletal Muscle Differentiation and Regeneration
N6-methyladenosine (m6A) RNA methylation has emerged as an important factor in various
biological processes by regulating gene expression. However, the dynamic profile, function …
biological processes by regulating gene expression. However, the dynamic profile, function …
Regulation of m6A RNA Methylation and Its Effect on Myogenic Differentiation in Murine Myoblasts
JN Chen, Y Chen, YY Wei, MA Raza, Q Zou, XY Xi… - Molecular Biology, 2019 - Springer
Abstract N 6-methyladenosine (m 6 A) has been identified as a conserved epitranscriptomic
modification of eukaryotic mRNAs, and plays important biological roles in the regulation of …
modification of eukaryotic mRNAs, and plays important biological roles in the regulation of …
[HTML][HTML] METTL3 Promotes the Differentiation of Goat Skeletal Muscle Satellite Cells by Regulating MEF2C mRNA Stability in am6A-Dependent Manner
S Zhao, J Cao, Y Sun, H Zhou, Q Zhu, D Dai… - International journal of …, 2023 - mdpi.com
The development of mammalian skeletal muscle is a highly complex process involving
multiple molecular interactions. As a prevalent RNA modification, N6-methyladenosine …
multiple molecular interactions. As a prevalent RNA modification, N6-methyladenosine …
METTL3‐Mediated m6A Methylation Regulates Muscle Stem Cells and Muscle Regeneration by Notch Signaling Pathway
Y Liang, H Han, Q Xiong, C Yang, L Wang… - Stem cells …, 2021 - Wiley Online Library
The Pax7+ muscle stem cells (MuSCs) are essential for skeletal muscle homeostasis and
muscle regeneration upon injury, while the molecular mechanisms underlying muscle stem …
muscle regeneration upon injury, while the molecular mechanisms underlying muscle stem …
[HTML][HTML] Regulation of RNA N6-methyladenosine modification and its emerging roles in skeletal muscle development
J Li, Y Pei, R Zhou, Z Tang, Y Yang - International Journal of …, 2021 - ncbi.nlm.nih.gov
Abstract N 6-methyladenosine (m 6 A) is one of the most widespread and highly conserved
chemical modifications in cellular RNAs of eukaryotic genomes. Owing to the development …
chemical modifications in cellular RNAs of eukaryotic genomes. Owing to the development …
METTL3 promotes proliferation and myogenic differentiation through m6A RNA methylation/YTHDF1/2 signaling axis in myoblasts
T Zhao, R Zhao, X Yi, R Cai, W Pang - Life Sciences, 2022 - Elsevier
Skeletal muscle development has an important impact on muscle-related diseases and
domestic animal meat production. The m 6 A RNA methylation is a common post …
domestic animal meat production. The m 6 A RNA methylation is a common post …
METTL3 Promotes the Differentiation of Goat Skeletal Muscle Satellite Cells by Regulating MEF2C mRNA Stability in am6A-Dependent Manner
Z Sen, J Cao, Y Sun, H Zhou, Q Zhu… - International …, 2023 - search.proquest.com
The development of mammalian skeletal muscle is a highly complex process involving
multiple molecular interactions. As a prevalent RNA modification, N6-methyladenosine (m 6 …
multiple molecular interactions. As a prevalent RNA modification, N6-methyladenosine (m 6 …
[HTML][HTML] N6-Methyladenosine Regulates the Expression and Secretion of TGFβ1 to Affect the Epithelial–Mesenchymal Transition of Cancer Cells
N6-methyladenosine (m6A) is the most abundant modification on eukaryotic mRNA, which
regulates all steps of the mRNA life cycle. An increasing number of studies have shown that …
regulates all steps of the mRNA life cycle. An increasing number of studies have shown that …