17b-estradiol and tamoxifen regulate a maxi-chloride channel from human placenta

M Henriquez, G Riquelme - The Journal of membrane biology, 2003 - Springer
Steroid hormones have been implicated in the modulation of several transport processes,
including conductive chloride transport in epithelial cells. Micromolar concentrations of these …

Apical Maxi-chloride channel from human placenta: 12 years after the first electrophysiological recordings

G Riquelme - Biological Research, 2006 - SciELO Chile
The Maxi-chloride channel was the first ion channel described by electrophysiological
methods in placenta. Because it is difficult to access a complex epithelium such as the …

Large chloride channel from pre-eclamptic human placenta

L Bernucci, F Umana, P Llanos, G Riquelme - Placenta, 2003 - Elsevier
Chloride transport involving conductive pathways participates in numerous epithelial
functions, such as membrane voltage maintenance, solute transport and cell volume …

Regulation of human placental chloride channel by arachidonic acid and other cis unsaturated fatty acids

G Riquelme, M Parra - American journal of obstetrics and gynecology, 1999 - Elsevier
Objective: Arachidonic acid has been implicated in the modulation of various transport
processes, including conductive chloride transport in brush border membranes in the human …

A chloride channel from human placenta reconstituted into giant liposomes

G Riquelme, A Stutzin, LF Barros… - American journal of …, 1995 - Elsevier
OBJECTIVE: Ion channels play important roles in epithelial transport, but they are difficult to
access for conventional electrophysiologic studies in intact placenta. The purpose of this …

Single-channel characterization of a nonselective cation channel from human placental microvillous membranes. Large conductance, multiplicity of conductance …

C Grosman, IL Reisin - The Journal of Membrane Biology, 2000 - Springer
The rate-limiting step for the maternofetal exchange of low molecular-weight solutes in
humans is constituted by transport across a single epithelial layer (syncytiotrophoblast) of …

Volume-activated chloride currents in HeLa cells are blocked by tamoxifen but not by a membrane impermeant quaternary analogue

M Sahebgharani, SP Hardy, AW Lloyd… - Cellular Physiology and …, 2001 - karger.com
Abstract Background/Aims: Tamoxifen has been shown to inhibit volume activated chloride
currents in many cell types. Tamoxifen has also been reported to inhibit a number of cation …

The maxi-chloride channel in human syncytiotrophoblast: a pathway for taurine efflux in placental volume regulation?

C Vallejos, G Riquelme - Placenta, 2007 - Elsevier
Taurine (Tau), the most abundant amino acid in fetal blood, is highly concentrated in human
placenta. During pregnancy, Tau is involved in the neurological development of the fetus …

Activation of Maxi Cl− channels by antiestrogens and phenothiazines in NIH3T3 fibroblasts

MA Valverde, SP Hardy, M Dı́az - Steroids, 2002 - Elsevier
The identification of alternative estrogen actions has been accumulating steadily over the
past two decades. Typically, these novel actions are not directly related to nuclear …

Factors affecting chloride conductance in apical membrane vesicles from human placenta

D Faller, MP Ryan - The Journal of membrane biology, 1992 - Springer
Apical membrane vesicles from human term placenta were isolated using a magnesium
precipitation technique, and the purity of the vesicles was assessed morphologically using …