Adenovirus vectors encoding carcinoembryonic antigen (Ad‐CEA) or costimulatory
molecules CD80, intercellular adhesion molecule‐1 (ICAM‐1) and leucocyte function …

Carcinoembryonic antigen (CEA) is an oncofetal antigen primarily detected in the peripheral
blood of cancer patients, particularly in those with colorectal cancer. CEA is considered a …

Abstract Dendritic cells (DCs), antigen-presenting cells capable of priming naive T cells to
specific antigens in an HLA-restricted fashion, have been demonstrated to induce protective …

Abstract Background Dendritic cells (DCs) are the professional antigen-presenting cells of
the immune system. As such they are currently used in clinical vaccination protocols in …

We conducted a clinical study of cancer vaccine therapy with dendritic cells (DCs) and HLA-
A24-restricted carcinoembryonic antigen (CEA)-derived peptide to assess the feasibility and …

The difficulty in obtaining a sufficient number of functional dendritic cells (DCs) is a well-
known serious problem in DCbased immunotherapy. Therefore, we used induced …

Induction of potent and sustained antitumor immunity depends on the efficient activation of
CD8+ and CD4+ T cells. Immunization using dendritic cells loaded with tumor antigens …

2544 Dendritic cells (DC) are the most potent antigen presenting cells of the immune
system, capable of inducing an effective anti-tumor immune response. They can be cultured …

Carcinoembryonic antigen (CEA) is strongly expressed in a vast majority of gastrointestinal
carcinomas. Recently, epitope peptides of CEA were identified. We have demonstrated HLA …

Purpose: The human carcinoembryonic antigen (CEA) is expressed in several tumor types,
including colorectal cancer, and is a tumor-associated antigen used as a target for antigen …