Synthesis of 3 '-3 '-linked oligonucleotides branched by a pentaerythritol linker is described.
The branched oligonucleotides were synthesized on a DNA/RNA synthesizer using a …

This Letter describes the synthesis and properties of double-stranded antisense
oligonucleotides connected with a pentaerythritol linker. We found that double-stranded …

We present our studies on the ability of several different nucleotide analogs as triplex-
forming oligonucleotides. The modifications tested include 4′-C-hydroxymethyl, LNA, 2 …

Multiple incorporations of 7-chloro-7-deaza-2′-deoxyguanosine in place of 2′-
deoxyguanosine have been performed into a triple helix-forming oligodeoxyribonucleotide …

The synthesis of 3 '-3 '-linked oligodeoxynucleotides (ODNs) with the anthraquinonyl group
at the junction point is described. The ODNs were synthesized on a DNA synthesizer using a …

The facile synthesis of 5′-5′-linked oligodeoxyribonucleotides (ODNs) with the potential
for triple-helix formation is described. ODNs containing 5-trifluoroethoxycarbonyl-2 …

The solid-phase synthesis of 5′-5′-linked oligonucleotides tethered via nucleic bases and
with opposite polarities has been performed using a modified dinucleoside bearing a …

For development of ideal antisense and antigene molecules, various chemical modifications
of oligonucleotides have been studied. However, despite their importance, there is only …

Novel nucleoside analogues containing 2′-deoxyinosine and aromatic rings, which are
connected by short linker groups, were synthesized and incorporated into …

In this paper, we describe the synthesis of the 3′-3′-linked oligonucleotides connected
with pentaerythritol composed of asymmetrical sequences. Stability of the triplexes between …